253866-86-3

Basic information

• Product Name: (2S,3S,6R)-6-benzenesulfonyloxy-2,3-epoxy-7-(4-fluorophenoxy)heptan-1-ol
• Synonyms: (2S,3S,6R)-6-benzenesulfonyloxy-2,3-epoxy-7-(4-fluorophenoxy)heptan-1-ol
• CAS NO: 253866-86-3
• Molecular Weight: 396.437
• Mol File: 253866-86-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S,6R)-6-benzenesulfonyloxy-2,3-epoxy-7-(4-fluorophenoxy)heptan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S,6R)-6-benzenesulfonyloxy-2,3-epoxy-7-(4-fluorophenoxy)heptan-1-ol(253866-86-3)
• EPA Substance Registry System: (2S,3S,6R)-6-benzenesulfonyloxy-2,3-epoxy-7-(4-fluorophenoxy)heptan-1-ol(253866-86-3)

Safety Data

• Hazardous Substances Data: 253866-86-3(Hazardous Substances Data)

Upstream product

• 253866-84-1 ethyl (2E,6R)-6-benzenesulfonyloxy-7-(4-fluorophenoxy)hept-1-en-1-oate 
• 253866-83-0 (2R)-2-benzenesulfonyloxy-1-(4-fluorophenoxy)-5-hexene 
• 254891-87-7 Benzenesulfonic acid (R)-1-(4-fluoro-phenoxymethyl)-4-oxo-butyl ester 
• 253866-82-9 (2R)-1-(4-fluoro)phenoxyhex-5-en-2-ol 
• 104605-97-2 (2R)-2,3-epoxy-1-(4-fluorophenoxy)propane 
• 591235-75-5 (S)-4-[(4-fluorophenoxy)methyl]-2,2-dimethyl-1,3-dioxolane 
• 104605-95-0 (2R)-1-(4-fluorophenoxy)propane-2,3-diol 
• 18123-82-5 2-(4-fluorophenoxymethyl)oxirane 
• 371-41-5 4-Fluorophenol 
• 253866-85-2 (2E,6R)-6-benzenesulfonyloxy-7-(4-fluorophenoxy)hept-1-en-1-ol 

Downstream Products

• 253866-87-4 (2R,3S,6R)-6-benzenesulfonyloxy-1-chloro-2,3-epoxy-7-(4-fluorophenoxy)heptane 
• 220623-71-2 (2S,5S)-trans-5-((4-fluorophenoxy)methyl)-2-(1-hydroxy-3-butyn-4-yl)tetrahydrofuran 
• 175212-45-0 (2S,5S)-trans-5-(4-fluorophenoxymethyl)-5-(4-N,O-bis-(phenoxycarbonyl)hydroxylamino-3-butyn-4-yl)tetrahydrofuran 
• 253866-88-5 (2S,5S)-2-ethynyl-5-[(4-fluorophenoxy)methyl]tetrahydrofuran 

Relevant articles and documents

A novel and simple asymmetric synthesis of CMI-977 (LDP-977): A potent anti-asthmatic drug lead

A practical gram scale asymmetric synthesis of CMI-977 is described. A tandem double elimination of an α-chlorooxirane and concomitant intramolecular nucleophilic substitution was used as the key step. Jacobsen hydrolytic kinetic resolution and Sharpless