25472-44-0 Usage
General Description
ETHYL 2-((ETHOXYCARBONYL)-METHYL)-1H-PYRROLE-3-CARBOXYLATE, also known as ethyl (1-ethyl-1H-pyrrol-2-yl) carbonate, is a chemical compound with the molecular formula C11H15NO4. It is a derivative of pyrrole, containing both ester and carbamate functional groups. ETHYL 2-((ETHOXYCARBONYL)-METHYL)-1H-PYRROLE-3-CARBOXYLATE is commonly used as a building block in the synthesis of pharmaceuticals and other organic compounds. It has potential applications in the field of medicinal chemistry due to its ability to modify the reactivity and binding properties of bioactive molecules.ETHYL 2-((ETHOXYCARBONYL)-METHYL)-1H-PYRROLE-3-CARBOXYLATE is a colorless to pale yellow liquid with a characteristic odor, and it is considered to be stable under normal conditions of use and storage. It is important to handle this compound with care, as it can be harmful if ingested or inhaled, and it may cause skin and eye irritation upon contact.
Check Digit Verification of cas no
The CAS Registry Mumber 25472-44-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,4,7 and 2 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 25472-44:
(7*2)+(6*5)+(5*4)+(4*7)+(3*2)+(2*4)+(1*4)=110
110 % 10 = 0
So 25472-44-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H15NO4/c1-3-15-10(13)7-9-8(5-6-12-9)11(14)16-4-2/h5-6,12H,3-4,7H2,1-2H3
25472-44-0Relevant articles and documents
Regioselective synthesis of functionalized pyrroles via gold(I)-catalyzed [3+2] cycloaddition of stabilized vinyl diazo derivatives and nitriles
Lonzi, Giacomo,Lopez, Luis A.
supporting information, p. 1948 - 1954 (2013/08/23)
The reaction of nitriles with alkenyldiazo compounds in the presence of gold catalysts provides functionalized pyrrole derivatives in moderate to high yields. This formal [3+2] cyclization reaction takes place with complete regioselectivity. The observed regiochemical outcome suggests the attack of the nitrile to the terminal position of the alkenylgold carbenoid (vinylogous reactivity). A broad range of nitriles (including those bearing functional groups) is compatible with this cyclization reaction. Copyright
