255730-18-8Relevant articles and documents
Absorption of the novel artemisinin derivatives artemisone and artemiside: Potential application of Pheroid technology
Steyn, J. Dewald,Wiesner, Lubbe,Du Plessis, Lissinda H.,Grobler, Anne F.,Smith, Peter J.,Chan, Wing-Chi,Haynes, Richard K.,Kotzé, Awie F.
, p. 260 - 266 (2011)
Artemisinins have low aqueous solubility that results in poor and erratic absorption upon oral administration. The poor solubility and erratic absorption usually translate to low bioavailability. Artemisinin-based monotherapy and combination therapies are
Artemisone - A highly active antimalarial drug of the artemisinin class
Haynes, Richard K.,Fugmann, Burkhard,Stetter, Joerg,Rieckmann, Karl,Heilmann, Hans-Dietrich,Chan, Ho-Wai,Cheung, Man-Ki,Lam, Wai-Lun,Wong, Ho-Ning,Croft, Simon L.,Vivas, Livia,Rattray, Lauren,Stewart, Lindsay,Peters, Wallace,Robinson, Brian L.,Edstein, Michael D.,Kotecka, Barbara,Kyle, Dennis E.,Beckermann, Bernhard,Gerisch, Michael,Radtke, Martin,Schmuck, Gabriele,Steinke, Wolfram,Wollborn, Ute,Schmeer, Karl,Roemer, Axel
, p. 2082 - 2088 (2007/10/03)
Artemisinin - the next generation: Efficacies of artemisone against the malaria parasite are substantially greater than those of the current artemisinin "gold standard", artesunate. Also, in contrast to most current artemisinins it displays low lipophilic
