72807-92-2Relevant articles and documents
Biomimetic metabolism of artelinic acid by chemical cytochrome P-450 model systems
Idowu, Olutosin R.,Lin, Ai J.,Grace, James M.,Peggins, James O.
, p. 1449 - 1454 (1997)
Purpose. To study the reaction of artelinic acid with chemical model systems of cytochrome P-450 as a means of obtaining authentic samples of the putative metabolites necessary for identification of the mammalian metabolites of artelinic acid. Methods. Ar
The behaviour of qinghaosu (artemisinin) in the presence of heme iron(II) and (III)
Haynes, Richard K.,Vonwiller, Simone C.
, p. 253 - 256 (2007/10/02)
With hemin [chlorprotoporphyrin IX iron(III)] or hemin/cysteine in aqueous MeCN, oxygen loss from the peroxide bridge of qinghaosu takes place to give a precursor to desoxoqinghaosu, a known malaria-inactive metabolite, in low yield. Ring-opened forms of
