2566-44-1

Basic information

• Product Name: 2-CYCLOPROPYLETHANOL
• Synonyms: Cyclopropaneethanol;2-CYCLOPROPYLETHANOL;Cyclopropaneethanol~(2-Hydroxyethyl)cyclopropane;(2-Hydroxyethyl)cyclopropane;2-Cyclopropylethanol, tech. 85%;2-Cyclopropylethan-1-ol
• CAS NO: 2566-44-1
• Molecular Formula: C₅H₁₀O
• Molecular Weight: 86.13
• EINECS: -0
• Product Categories: Cycloalkanes
• Mol File: 2566-44-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 137-138°C
• Flash Point: 47°C
• Appearance: /
• Density: 0.975 g/cm₃
• Vapor Pressure: 5.13mmHg at 25°C
• Refractive Index: 1.4355
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform, Methanol
• PKA: 15.16±0.10(Predicted)
• Water Solubility: Miscible with water.
• BRN: 2036028
• CAS DataBase Reference: 2-CYCLOPROPYLETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CYCLOPROPYLETHANOL(2566-44-1)
• EPA Substance Registry System: 2-CYCLOPROPYLETHANOL(2566-44-1)

Safety Data

• Hazard Codes: Xn
• Statements: 10-36-22
• Safety Statements: 16-23-36/37/39-26
• RIDADR: 1987
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 2566-44-1(Hazardous Substances Data)

Usage

Description

2-Cyclopropylethanol is an organic compound characterized by the presence of a cyclopropane ring and an ethanol group. It is a versatile chemical intermediate with potential applications in various industries due to its unique structural properties.

Uses

Used in Pharmaceutical Industry:
2-Cyclopropylethanol is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows for the creation of complex molecules with specific biological activities.
Used in Chemical Synthesis:
2-Cyclopropylethanol is used as a starting material for the preparation of (2-bromo-ethyl)-cyclopropane by reacting with phosphorus tribromide. This reaction is an example of its utility in organic chemistry, where it can be further modified to produce a range of different compounds.

InChI:InChI=1/C5H10O/c6-4-3-5-1-2-5/h5-6H,1-4H2

Upstream product

• 67133-88-4 5-iodo-1-pentanol 
• 530133-47-2 methyl 3-cyclopropyl-2,3-epoxypropionate 
• 1489-69-6 Cyclopropanecarboxaldehyde 
• 14902-14-8 -triphenyl-phosphoran 
• 5239-82-7 cyclopropylacetic acid 
• 75-21-8 oxirane 
• 4333-56-6 cyclopropyl bromide 
• 34108-21-9 methyl cyclopropylacetate 
• 66688-08-2 1,1-Di-(2-cyclopropylethoxy)methan 
• 53432-87-4 ethyl 2-cyclopropyl acetate 
• 693-86-7 ethenylcyclopropane 
• 627-27-0 homoalylic alcohol 
• 75-11-6 diiodomethane 

Downstream Products

• 36982-56-6 (2-bromoethyl)cyclopropane 
• 5239-82-7 cyclopropylacetic acid 
• 1759-53-1 cyclopropanecarboxylic acid 
• 477933-12-3 1-(2-cyclopropylethyl)-6-fluoro-1H-benzo[d][1,3]oxazine-2,4-dione 
• 1191923-56-4 4-(2-cyclopropylethoxy)-N,N-diethylbenzamide 
• 1236764-20-7 1-(2-cyclopropylethoxy)-4-nitrobenzene 
• 63064-31-3 4-methylphenyl sulfonic acid (2-cyclopropylethyl) ester 
• 347846-59-7 2-Benzyloxy-1-[(3S,4S)-4-[3-(2-cyclopropylethoxy)-4-methoxyphenyl]-3-((1R)-1-hydroxyethyl)-3-methylpyrrolidin-1-yl]ethanone 
• 56105-19-2 2-cyclopropylacetaldehyde 
• 335449-19-9 (2-iodoethyl) cyclopropane 
• 5618-03-1 3-cyclopropanepropionic acid 
• 1191-96-4 ethylcyclopropane 
• 915016-55-6 methyl 4-(2-cyclopropylethoxy)benzoate 
• 50438-91-0 Thiobenzoesaeure-O-2-cyclopropylaethylester 

Relevant articles and documents

PROCESSES FOR PREPARATION OF CYCLOPROPYLETHANOL, CYCLO-PROPYLACETONITRILE AND INTERMEDIATES OF BOTH

A process for preparation of cyclopropylethanol, which comprises subjecting a 3-cyclopropyl-2,3-epoxypropionic acid ester to solvolysis, treating the product of the solvolysis with an acid to obtain cyclopropylacetaldehyde, and reducing the obtained cyclopropylacetaldehyde; and a process for preparation of cyclopropylacetonitrile, which comprises subjecting a 3-cyclopropyl-2,3-epoxypropionic acid ester to solvolysis in the presence of a base, treating the product of the solvolysis with an acid to obtain cyclopropylacetaldehyde, reacting the obtained cyclopropylacetaldehyde with hydroxylamine or salts thereof to obtain cyclopropaneacetaldehyde oxime, and reacting the obtained cyclopropaneacetaldehyde oxime with acetic anhydride. According to the present invention, cyclopropylethanol and cyclopropylacetonitrile can be prepared at low costs and industrially advantageously.

METHOD FOR TREATING ANXIETY

The present invention provides a method for treating anxiety in humans using azacyclic or azabicyclic compounds.