26275-20-7

Basic information

• Product Name: 6-deoxy-1,2-O-isopropylidene-6-(4'-methylbenzene)sulfonyloxy-D-glucofuranose
• Synonyms: 6-deoxy-1,2-O-isopropylidene-6-(4'-methylbenzene)sulfonyloxy-D-glucofuranose
• CAS NO: 26275-20-7
• Molecular Weight: 374.412
• Mol File: 26275-20-7.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 6-deoxy-1,2-O-isopropylidene-6-(4'-methylbenzene)sulfonyloxy-D-glucofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 6-deoxy-1,2-O-isopropylidene-6-(4'-methylbenzene)sulfonyloxy-D-glucofuranose(26275-20-7)
• EPA Substance Registry System: 6-deoxy-1,2-O-isopropylidene-6-(4'-methylbenzene)sulfonyloxy-D-glucofuranose(26275-20-7)

Safety Data

• Hazardous Substances Data: 26275-20-7(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 18549-40-1 1,2-O-isopropylidene-α-D-glucofuranose 
• 582-52-5 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 2280-44-6 D-Glucose 
• 2595-05-3 Diacetone D-glucose 
• 50-99-7 D-glucose 

Downstream Products

• 5458-82-2 3,5-Di-O-acetyl-1,2-O-isopropylidene-6-O-p-toluenesulfonyl-α-D-glucofuranose 
• 84856-99-5 O³,O⁵-dibenzoyl-O¹,O²-isopropylidene-O⁶-(toluene-4-sulfonyl)-α-D-glucofuranose 
• 20113-43-3 1,2,3,4-tetra-O-acetyl-6-O-p-tolylsulfonyl-α-D-glucopyranose 
• 6619-10-9 1,2,3,4-tetra-O-acetyl-6-O-p-tolylsulfonyl-β-D-glucopyranose 
• 65371-16-6 3,5-di-O-acetyl-6-deoxy-1,2-O-isopropylidene-6-azido-α-D-glucofuranose 
• 20847-06-7 O⁶-(toluene-4-sulfonyl)-D-glucose 
• 34322-91-3 1,2:3,5-bis-O-(1-methylethylidene)-6-(p-tolylsulfonyl)-α-D-glucofuranose 
• 7595-86-0 O³,O⁵-((Ξ)-benzylidene)-O¹,O²-isopropylidene-O⁶-(toluene-4-sulfonyl)-α-D-glucofuranose 
• 24384-87-0 6-amino-6-deoxy-1,2-O-isopropylidene-α-D-glucofuranose 
• 3458-06-8 6-sulfo-6-deoxy-D-glucose 
• 17668-66-5 6-deoxy-1,2-O-isopropylidene-α-D-glucofuranose 
• 20847-05-6 6-Azido-6-desoxy-D-glucopyranose 
• 84715-86-6 1,2-O-isopropylidene-6-O-p-tolylsulfonyl-α-D-glucofuranose 3,5-thioxophosphite 
• 84856-98-4 6-(Adenin-9-yl)-6-deoxy-3,5-di-O-isopropylidene-α-D-glucofuranose 

Relevant articles and documents

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Synthesis, characterization, and antimicrobial activities of novel monosaccharide-containing Schiff base ligands

Four new chiral Schiff base ligands (3a–4a, 3b–4b) have been prepared using aminoisopropylidene derivatives of glucose and aminochloralose derivatives of mannose. The synthesized compounds 1 and 2 were characterized by nuclear magnetic resonance (1/

Synthesis of [18F]-6-deoxy-6-fluoro-D-glucose ([ 18F]6FDG), a potential tracer of glucose transport

With the goal of developing a PET radioligand for the in vivo assessment of glucose transport, 6-deoxy-6-[18F]fluoro-D-glucose ([ 18F]6FDG) was prepared in two steps from 18F-. Starting with D-glucose, the tosyl- and mesyl-derivatives of 3,5-O-benzylidene-1,2-O-isopropylidene-α-D-glucofuranose were prepared by known methods. Reaction of either of these precursors with 18F - resulted in the formation of 3,5-O-benzylidene-6-deoxy-O-[ 18F]-fluoro-1,2-O-isopropylidene-α-D-glucofuranose in high yield. Subsequent hydrolysis resulted in the production of [18F]6FDG. Under optimal conditions, [18F]6FDG is produced 60-70 min after end of bombardment (EOB) in 71 ± 12% yield (decay corrected, based upon fluoride) with a radiochemical purity of ≥96%. Preliminary experiments have indicated that [18F]6FDG may be a more representative in vivo tracer for the glucose transporter than 2FDG. Copyright