26311-41-1

Basic information

• Product Name: Benzoic acid, 2-pentyl-, methyl ester
• CAS NO: 26311-41-1
• Molecular Formula: C13H18O2
• Molecular Weight: 206.285
• Mol File: 26311-41-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-pentyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-pentyl-, methyl ester(26311-41-1)
• EPA Substance Registry System: Benzoic acid, 2-pentyl-, methyl ester(26311-41-1)

Safety Data

• Hazardous Substances Data: 26311-41-1(Hazardous Substances Data)

Upstream product

• 308796-10-3 (1-pentyl)zinc(II) bromide 
• 4122-56-9 methyl o-formylbenzoate 
• 122654-40-4 4,4-Dimethyl-2-(2-pentyl-phenyl)-4,5-dihydro-oxazole 
• 693-25-4 n-pentylmagnesium bromide 
• 100368-67-0 2-Amyl-benzamid 
• 57598-33-1 2-(2-methoxyphenyl)-4,4-dimethyl-2-oxazoline 
• 110683-65-3 ((E)-2-Pent-1-enyl)-benzoic acid methyl ester 

Downstream Products

• 110698-31-2 (E)-3-(2-Pentyl-phenyl)-N-[3-(1H-tetrazol-5-yl)-2,3-dihydro-benzo[1,4]dioxin-5-yl]-acrylamide 
• 103178-04-7 2-Pentyl-N-[3-(1H-tetrazol-5-yl)-2,3-dihydro-benzo[1,4]dioxin-5-yl]-benzamide 
• 103175-75-3 4-Pentyl-N-[3-(1H-tetrazol-5-yl)-2,3-dihydro-benzo[1,4]dioxin-5-yl]-benzamide 
• 110683-35-7 o-amylcinnamic acid 
• 59059-43-7 2-n-pentylbenzaldehyde 
• 26311-42-2 2-n-pentylbenzoic acid 
• 151888-64-1 2-Diphenylacetyl-5-pentyl-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid methyl ester 
• 1026260-46-7 2-Formylamino-2-(2-pentyl-benzyl)-malonic acid diethyl ester 
• 1026802-35-6 Methanesulfonic acid 2-pentyl-benzyl ester 
• 110683-66-4 o-amylbenzyl alcohol 

Relevant articles and documents

Nickel-Catalyzed C-O Bond-Cleaving Alkylation of Esters: Direct Replacement of the Ester Moiety by Functionalized Alkyl Chains

Two efficient protocols for the nickel-catalyzed aryl-alkyl cross-coupling reactions using esters as coupling components have been established. The methods enable the selective oxidative addition of nickel to acyl C-O and aryl C-O bonds and allow the aryl-alkyl cross-coupling via decarbonylative bond cleavage or through cleavage of a C-O bond with high efficiency and good functional group compatibility. The protocols allow the streamlined, unconventional utilization of widespread ester groups and their precursors, carboxylic acids and phenols, in synthetic organic chemistry.

New potent antagonists of leukotrienes C4 and D4. 1. Synthesis and structure-activity relationships

(p-Amylcinnamoyl)anthranilic acid (3a) had moderate antagonist activities against LTD4-induced smooth muscle contraction on guinea pig ileum and LTC4-induced bronchoconstriction in anesthetized guinea pigs. Modifications were made in the hydrophobic part (cinnamoyl moiety) and the hydrophilic part (anthranilate moiety) of 3a. A series of 8-(benzoylamino)-2-tetrazol-5-yl-1,4-benzodioxans and 8-(benzoylamino)-2-tetrazol-5-yl-4-oxo-4H-1-benzopyrans were revealed to be potent antagonists of leukotrienes C4 and D4. Among both series, ONO-RS-347 (18k) and ONO-RS411 (19h) were the most potent and orally active antagonists, respectively. Structure-activity relationships are discussed.