2650-67-1

Basic information

• Product Name: Z-GLN-OME
• Synonyms: N-ALPHA-CARBOBENZOXY-L-GLUTAMINE ALPHA-METHYL ESTER;Z-GLUTAMINE-OME;Z-GLN-OME;Z-L-GLUTAMINE METHYL ESTER;N2-[(Phenylmethoxy)Carbonyl]-L-Glutamine Methyl Ester;Z-L-Gln-OMe;Z-L-glutamine methyl ester≥ 98% (HPLC)
• CAS NO: 2650-67-1
• Molecular Formula: C₁₄H₁₈N₂O₅
• Molecular Weight: 294.3
• Mol File: 2650-67-1.mol
• Article Data: 12

Chemical Properties

• Melting Point: 138-139 °C
• Boiling Point: 542.1±50.0 °C(Predicted)
• Appearance: /
• Density: 1.235±0.06 g/cm3(Predicted)
• Storage Temp.: -15°C
• PKA: 10.83±0.46(Predicted)
• CAS DataBase Reference: Z-GLN-OME(CAS DataBase Reference)
• NIST Chemistry Reference: Z-GLN-OME(2650-67-1)
• EPA Substance Registry System: Z-GLN-OME(2650-67-1)

Safety Data

• Hazardous Substances Data: 2650-67-1(Hazardous Substances Data)

Usage

Chemical Properties

White solid

Upstream product

• 186581-53-3 diazomethane 
• 2650-64-8 Cbz-L-Gln 
• 67-56-1 methanol 
• 5672-83-3 Z-L-GluOMe 
• 79-20-9 acetic acid methyl ester 
• 74-88-4 methyl iodide 
• 501035-53-6 Z-Asn(Trt)-OMe 
• 4668-37-5 N-(benzyloxycarbonyl)asparagine methyl ester 
• 56-85-9 L-glutamine 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 4008-03-1 N²-benzyloxycarbonyl-L-glutamine hydrazide 
• 32668-14-7 L-glutamine methyl ester monohydrochloride 
• 24666-55-5 3-(benzyloxycarbonyl)-amino-2,6-dioxopiperidine 
• 30134-53-3 (R)-2-Benzyloxycarbonylamino-4-cyano-butyric acid methyl ester 
• 42259-95-0 (2-Oxo-pyrrolidin-3-yl)-carbamic acid benzyl ester 
• 636-65-7 glutamine 
• 56-85-9 L-glutamine 
• 199006-30-9 Z-Gln(Tr)-OMe 
• 5672-83-3 Z-L-GluOMe 
• 118507-50-9 (3S)-3-benzyloxycarbonylamino-2-pyrrolidinone 
• 1033726-45-2 methyl 3-benzyloxycarbonyl-(tetrahydro)pyrimidin-2-one-4(S)-carboxylate 
• 1417900-08-3 (3S)-3-[(benzyloxycarbonyl)amino]-1-amino-piperidin-2-one 
• 1417900-09-4 (3S)-3-[(benzyloxycarbonyl)amino]-1-(methylamino)piperidin-2-one 
• 1417900-16-3 (3S)-1-{[3-(benzyloxycarbonyl)amino]-2-oxopiperidin-1-yl}urea 

Relevant articles and documents

A Novel compound

The present invention relates to a novel compound and uses thereof. The novel compound according to the present invention, by inducing the activation of an MKP-1 protein, has an effect of inhibiting inflammatory responses very effectively that occur in respiratory diseases by blocking cell signaling in the order of p38/CK2alpha/NF-kappaB. Accordingly, it is possible to prevent, alleviate or treat the respiratory diseases by oral administration of the novel compound of the present invention.

Substituted 2-(2, 6-Dioxopiperidin-3-yl)-1-method of preparing oxoisoindolines

The present invention concerns new processes for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines which are useful for preventing or treating diseases or conditions related to an abnormally high level or activity of TNF±. The i

Combinatorial synthesis of 3,5-Dimethylene substituted 1,2,4-Triazoles

Combinatorial cyclizations of imidates and hydrazides with methylene linked R groups, generated from the corresponding nitriles and carboxylic acids, respectively, provided a large library of 3,5-dimethylene substituted 1,2,4- trizoles. 2011 Bentham Science Publishers Ltd.