26774-88-9

Basic information

• Product Name: (R)-(-)-2-(2,5-Dihydrophenyl)glycine
• Synonyms: (R)-alpha-aminocyclohexa-1,4-diene-1-acetic acid;D-(-)-alpha-2,5-Dihydrophenylglycine;(R)-(-)-2-(2,5-DIHYDROPHENYL)GLYCINE, 98;D-(-)-Dihydro-alpha-phenylglycine;(r)-à-amino-1-(1,4-cyclohexadienyl)acetic acid;(r)-α-amino-1,4-cyclohexadiene-1-acetic acid;L--Dihydrophenylglycine;D(-)-DIHYDROXYPHENYLGLYCINE
• CAS NO: 26774-88-9
• Molecular Formula: C₈H₁₁NO₂
• Molecular Weight: 153.18
• EINECS: 247-999-1
• Product Categories: Pharmaceutical Intermediates
• Mol File: 26774-88-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 280 °C (dec.)(lit.)
• Boiling Point: 276.1°C (rough estimate)
• Flash Point: 122.8 °C
• Appearance: White powder
• Density: 1.1577 (rough estimate)
• Vapor Pressure: 0.00107mmHg at 25°C
• Refractive Index: -155 ° (C=1, 1mol/L HCl)
• Storage Temp.: -20°C
• Solubility: Aqueous Acid (Slightly)
• PKA: 2.17±0.10(Predicted)
• BRN: 2091420
• CAS DataBase Reference: (R)-(-)-2-(2,5-Dihydrophenyl)glycine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(-)-2-(2,5-Dihydrophenyl)glycine(26774-88-9)
• EPA Substance Registry System: (R)-(-)-2-(2,5-Dihydrophenyl)glycine(26774-88-9)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 26774-88-9(Hazardous Substances Data)

Usage

Chemical Properties

white powder

Uses

(R)-(-)-2-(2,5-Dihydrophenyl)glycine is a cycohexadiene based amino acid used in the preparation of cephalosporin-type antibiotics such as Cephradine (C261800).

InChI:InChI=1/C8H11NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h1-2,5,7H,3-4,9H2,(H,10,11)/t7-/m1/s1

Upstream product

• 54855-97-9 (R)-α-Ureido-1,4-cyclohexadien-1-yl-essigsaeure 

Downstream Products

• 20763-30-8 D-2-amino-2-(1,4-cyclohexadien-1-yl)acetic acid 
• 30959-67-2 Cefradine 
• 104236-44-4 methyl (R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetate 
• 57872-59-0 (R)-2-(tert-butoxycarbonylamino)-2-(cyclohexa-1,4-dienyl)acetic acid 
• 54855-97-9 (R)-α-Ureido-1,4-cyclohexadien-1-yl-essigsaeure 

Relevant articles and documents

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