27048-28-8Relevant articles and documents
A half sandwich ruthenium(II) complex with n-4,6-dimethyl-2-pyrimidinylimidazole: Synthesis, crystal structure and application in N-Alkylation of amines with alcohols
Li, Hong-Mei,Xu, Chen,Wang, Zhi-Qiang,Fu, Wei-Jun
, p. 2557 - 2560 (2015/10/19)
-
Fe2O3-supported nano-gold catalyzed one-pot synthesis of N-alkylated anilines from nitroarenes and alcohols
Peng, Qiling,Zhang, Yan,Shi, Feng,Deng, Youquan
supporting information; experimental part, p. 6476 - 6478 (2011/06/28)
Here, we show the one-step synthesis of N-alkylated anilines from nitrobenzenes and alcohols catalyzed by nano-gold catalyst. The yields to N-alkylated anilines were ～90% under mild conditions. The mechanism of this reaction was explored. It shows promise for clean and simple synthesis of N-alkylated anilines.
Identification and characterization of amino-piperidinequinolones and quinazolinones as MCHr1 antagonists
Blackburn, Christopher,LaMarche, Matthew J.,Brown, James,Che, Jennifer Lee,Cullis, Courtney A.,Lai, Sujen,Maguire, Martin,Marsilje, Thomas,Geddes, Bradley,Govek, Elizabeth,Kadambi, Vivek,Doherty, Colleen,Dayton, Brian,Brodjian, Sevan,Marsh, Kennan C.,Collins, Christine A.,Kym, Philip R.
, p. 2621 - 2627 (2007/10/03)
Several potent, functionally active MCHr1 antagonists derived from quinolin-2(1H)-ones and quinazoline-2(1H)-ones have been synthesized and evaluated. Pyridylmethyl substitution at the quinolone 1-position results in derivatives with low-nM binding potency and good selectivity with respect to hERG binding.
