271-92-1

Basic information

• Product Name: Furo[3,2-c]pyridine
• Synonyms: Furo[3,2-c]pyridine;furo[3;5-Azabenzo[b]furan, 5-Aza-1-benzofuran;furo[3,2-c]pyridine(WXC07719)
• CAS NO: 271-92-1
• Molecular Formula: C₇H₅NO
• Molecular Weight: 119.1207
• Mol File: 271-92-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 197.918 °C at 760 mmHg
• Flash Point: 77.771 °C
• Appearance: /
• Density: 1.196 g/cm³
• PKA: 4.40±0.30(Predicted)
• CAS DataBase Reference: Furo[3,2-c]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: Furo[3,2-c]pyridine(271-92-1)
• EPA Substance Registry System: Furo[3,2-c]pyridine(271-92-1)

Safety Data

• Hazardous Substances Data: 271-92-1(Hazardous Substances Data)

Usage

General Description

Furo[3,2-c]pyridine is a chemical compound with a unique fused ring structure combining a furan and pyridine ring. It is commonly used in pharmaceutical research and drug development due to its potential biological activities and pharmacological properties. Furo[3,2-c]pyridine derivatives have been studied for their potential as anticancer, antimicrobial, and anti-inflammatory agents. They have also been investigated for their potential to modulate various biological targets, including kinases, receptors, and enzymes. The unique structural features of furo[3,2-c]pyridine make it an interesting target for further research and development of novel pharmaceutical compounds.

Upstream product

• 119924-26-4 (E)-3-(2-furanyl)-2-propenoyl azide 
• 33007-15-7 7-hydroxy-6,7-dihydro-5H-furo[3,2-c]pyridin-4-one 
• 46265-05-8 2-(2-amino-1-hydroxy-ethyl)-furan-3-carboxylic acid ethyl ester 
• 539-47-9 3-(fur-2-yl)crotonic acid 
• 20689-54-7 3-furanylacryloyl chloride 
• 26956-43-4 5H-furo[3,2-c]pyridin-4-one 
• 57420-06-1 furo<3,2-c>pyridine N-oxide 
• 76312-04-4 4-Bromofuro<3,2-c>pyridin 
• 6921-34-2 benzylmagnesium chloride 
• 92404-70-1 3-bromofuro<3,2-c>pyridine 
• 31270-80-1 4-chlorofuro[3,2-c]pyridine 
• 33279-80-0 3-acetoxy-2,3-dihydro-furo[3,2-c]pyridine 

Downstream Products

• 112372-07-3 furo<3,2-c>pyridine-2-carboxaldehyde 
• 860618-06-0 1-(furo[3,2-c]pyridin-2-yl-carbonyl-3-(3-fluoro-4-pentyloxy)-phenyl)thiourea 
• 860618-05-9 1-(furo[3,2-c]pyridin-2-yl-carbonyl-3-(3-fluoro-4-pentyloxy)-phenyl)thiourea hydrochloride 
• 1031849-09-8 5-aminofuro[3,2-c]pyridin-5-ium 2,4-dinitrobenzenolate 
• 117612-42-7 2-sulfamoylfuro[3,2-c]pyridine 
• 609-70-1 4-hydroxynicotinic acid 
• 112372-13-1 2-cyanofuro<3,2-c>pyridine 
• 142503-01-3 2-phenylthio-3-bromofuro<3,2-c>pyridine 
• 142503-10-4 3-(2-phenylthioethynyl)-4-pyridinol 
• 188939-20-0 5-isopropoxycarbonylfuro[3,2-c]pyridinio-4-(p-methoxyphenyl)methoxide 
• 188939-17-5 5-isopropoxycarbonylfuro[3,2-c]pyridinio-4-phenylmethoxide 
• 188939-27-7 4-Furo[3,2-c]pyridin-4-ylmethyl-benzonitrile 
• 188939-22-2 4-(4-Methoxy-benzyl)-furo[3,2-c]pyridine 

Relevant articles and documents

SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF

Provided herein are small molecule activators of Nicotinamide Phosphoribosyltransferase (NAMPT), compositions comprising the compounds, and methods of using the compounds and compositions.

AZABENZOFURAN SUBSTITUTED THIOUREAS; INHIBITORS OF VIRAL REPLICATION

The present invention provides compounds of Formula: (1), wherein the variables Ar, A1, A2, A3, A4, R5, R6, R7, V, W, X, and Y are defined herein. Certain compounds of Formula (1

Furopyridines. XII. Reaction of 3-Bromo, 2-Phenylthio and 2-Phenylthio-3-bromo Derivatives of Furo-, Furo-, Furo- and Furopyridine with Several Alkyllithiums

This paper describes reactions of 3-bromo- 1a-d, 2-phenylthio- 5a-d and 2-phenylthio-3-bromofuropyridines 6a-d with n-butyl-, t-butyl- and methyllithium and lithioacetonitrile.Lithiation of compounds 1a-d with n-butyl- or methyllithium gave the parent furopyridines 2a-d and o-ethynylpyridinols 3a-d.Reaction of compounds 5a-d with methyllithium afforded o-(phenylthioethynyl)pyridinols 7a-d, which were also yielded by reaction of compounds 6a-d with t-butyl- or methyllithium.The phenylthio group in compounds 7a-d were substituted with t-butyl group by the reaction with excess t-butyllithium.In contrast, 2-phenylthio group in compounds 5a-d and 6a-d was substituted with cyanomethyl group by reaction with lithioacetonitrile to give compounds 11a-d and 10b,c respectively.