271247-48-4Relevant articles and documents
Pyridazine based inhibitors of p38 MAPK
McIntyre, Charles J,Ponticello, Gerald S,Liverton, Nigel J,O'Keefe, Stephen J,O'Neill, Edward A,Pang, Margaret,Schwartz, Cheryl D,Claremon, David A
, p. 689 - 692 (2007/10/03)
Trisubstituted pyridazines were synthesized and evaluated as in vitro inhibitors of p38 MAPK. The most active isomers were those possessing an aryl group α and a heteroaryl group β relative to the nitrogen atom in the 2-position of the central pyridazine.