27200-79-9

Basic information

• Product Name: (4-BROMO-PHENYL)-ACETALDEHYDE
• Synonyms: 2-(4-BROMOPHENYL)ACETALDEHYDE;(4-BROMO-PHENYL)-ACETALDEHYDE;2-(4-Bromophenyl)ethanal;4-Bromobenzeneacetaldehyde;Benzeneacetaldehyde,4-bromo-;Acetaldehyde, (p-bromophenyl)-
• CAS NO: 27200-79-9
• Molecular Formula: C₈H₇BrO
• Molecular Weight: 199.04
• Product Categories: Aromatic Aldehydes & Derivatives (substituted)
• Mol File: 27200-79-9.mol
• Article Data: 60

Chemical Properties

• Melting Point: 96-97 °C(Solv: 1,4-dioxane (123-91-1); ethyl ether (60-29-7))
• Boiling Point: 267.499 °C at 760 mmHg
• Flash Point: 99.676 °C
• Appearance: /
• Density: 1.466 g/cm³
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: (4-BROMO-PHENYL)-ACETALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-BROMO-PHENYL)-ACETALDEHYDE(27200-79-9)
• EPA Substance Registry System: (4-BROMO-PHENYL)-ACETALDEHYDE(27200-79-9)

Safety Data

• Hazardous Substances Data: 27200-79-9(Hazardous Substances Data)

Usage

Uses

(4-Bromophenyl)acetaldehyde is a useful reagent in the synthesis and cytotoxic activity of certain trisubstituted azetidin-2-one derivsatives as cis-restricted combretastatin A-4 analogs.

Upstream product

• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 4412-42-4 1-Bromo-4-(2,2-dichloro-ethyl)-benzene 
• 106-40-1 4-bromo-aniline 
• 1009867-14-4 1-(4-bromophenyl)-2-iodo-ethanol 
• 41841-16-1 (4-bromo-phenyl)-acetic acid methyl ester 
• 1878-68-8 2-(4-bromophenyl)-acetic acid 
• 148684-05-3 2-(4-bromophenyl)oxirane 
• 32017-76-8 (+/-)-2-(4-bromophenyl)oxirane 
• 135879-71-9 [(E)-2-(4-Bromo-phenyl)-vinyl]-carbamic acid methyl ester 
• 872-36-6 vinylene carbonate 
• 5467-74-3 4-Bromophenylboronic acid 
• 59436-09-8 1-bromo-4-(2-methoxyethenyl)benzene 
• 1122-91-4 4-bromo-benzaldehyde 
• 4009-98-7 (methoxymethyl)triphenylphosphonium chloride 

Downstream Products

• 72680-69-4 2--4'-bromostyrene 
• 1883-96-1 N-benzylidenepyridin-2-amine 
• 936494-74-5 2-(4-bromophenyl)-2-(hydroxymethyl)propane-1,3-diol 
• 1006606-06-9 CF₃O₃S^(1-)*C₂₄H₁₈Br₂N⁽¹⁺⁾ 
• 1023700-93-7 (S)-2-[2-(4-bromo-phenyl)-ethylamino]-4-methyl-pentanoic acid cyclopentyl ester 
• 1233823-75-0 (S)-(+)-methyl 4-(4-bromophenyl)-6-methyl-1,4-dihydropyridazine-5-carboxylate 
• 1429332-49-9 C₈H₅BrCl₂O 
• 16807-64-0 3-(4-bromophenyl)-2H-chromen-2-one 
• 1565756-66-2 N¹-(4-bromophenethyl)-N³,N³-dimethylpropane-1,3-diamine 
• 1584128-35-7 (2S,3S)-3-[N-(tert-butoxycarbonyl)amino]-3-(furan-2-yl)-2-(4-bromophenyl)propanol 
• 13178-00-2 4-(4-bromophenyl)-1-phenyl-1H-1,2,3-triazole 

Relevant articles and documents

Gold nanoparticles supported on magnesium oxide nanorods for oxidation of alcohols

Gold nanoparticles supported on magnesium oxide nanorods (Au-MgO) have been synthesised by a solution based chemical reduction method. Au-MgO nanorods were found to be an efficient heterogeneous catalyst for oxidation of alcohols with hydrogen peroxide in aqueous medium at room temperature. To find out the best reaction conditions for oxidation, optimization of catalyst quantity, solvent, mole equivalence of hydrogen peroxide were carried out. The scope of the reaction was extended to several aromatic and aliphatic alcohols, product yields were quantified by gas chromatography (GC) and GC/mass spectroscopy. Heterogeneity and reusability tests were performed. The use of water as a solvent and hydrogen peroxide as co-catalyst at room temperature makes the reaction interesting from sustainable development point of view.

Aerobic epoxidation of styrene over Zr-based metal-organic framework encapsulated transition metal substituted phosphomolybdic acid

Catalytic epoxidation of styrene with molecular oxygen is regarded as an eco-friendly alternative to producing industrially important chemical of styrene oxide (STO). Recent efforts have been focused on developing highly active and stable heterogeneous catalysts with high STO selectivity for the aerobic epoxidation of styrene. Herein, a series of transition metal monosubstituted heteropolyacid compounds (TM-HPAs), such as Fe, Co, Ni or Cu-monosubstituted HPA, were encapsulated in UiO-66 frameworks (denoted as TM-HPA@UiO-66) by direct solvothermal method, and their catalytic properties were investigated for the aerobic epoxidation of styrene with aldehydes as co-reductants. Among them, Co-HPA@UiO-66 showed relatively high catalytic activity, stability and epoxidation selectivity at very mild conditions (313 K, ambient pressure), that can achieve 82 % selectivity to STO under a styrene conversion of 96 % with air as oxidant and pivalaldehyde (PIA) as co-reductant. In addition, the hybrid composite catalyst can also efficiently catalyze the aerobic epoxidation of a variety of styrene derivatives. The monosubstituted Co atoms in Co-HPA@UiO-66 are the main active sites for the aerobic epoxidation of styrene with O2/PIA, which can efficiently converting styrene to the corresponding epoxide through the activation of the in-situ generated acylperoxy radical intermediate.

Kinetic Resolution of Neopentylic Secondary Alcohols by Cu-H-Catalyzed Enantioselective Silylation with Hydrosilanes

A nonenzymatic kinetic resolution of sterically congested alcohols having a quaternary carbon atom in the β-position is reported. The catalyst system CuCl/NaOtBu/(R,R)-Ph-BPE together with a 3,5-xylyl-substituted tertiary hydrosilane enable enantioselective silylation of the hydroxy group. Several alcohols are obtained with good to excellent selectivity factors, and there are no other known straightforward methods to access these motifs.