27605-76-1Relevant articles and documents
Preparation method of probenazole
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Paragraph 0031; 0037-0041; 0047-0050, (2020/02/10)
The invention provides a preparation method of probenazole. The method comprises the following steps: by taking saccharin as an initial raw material, chlorinating with thionyl chloride in 1, 4-dioxaneto obtain a chloride, adding a high-boiling-point solvent to remove the solvent dioxane and excessive thionyl chloride, directly carrying out substitution reaction with a sodium salt or a potassium salt of allyl alcohol, and carrying out centrifugal desalination and cooling recrystallization to directly obtain high-purity probenazole. The preparation method is capable of solveing the problem of difficult kettle rotation caused by chloride solidification in the prior art, avoiding the generation of allyl chloride during etherification by allyl alcohol, and reducing the water washing procedurein the traditional method. Compared with the traditional method, the advantages are that the preparation method is simple and convenient to operate, high in yield, less in three wastes and high in purity of the obtained product, greatly saves the production cost and the environmental protection cost, and is easy to realize industrialization.
Synergistic Combinations Of Active Ingredients
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, (2012/02/15)
The present invention relates to novel active compound combinations comprising, firstly, at least one known compound of the formula (I) in which R1 and A have the meanings given in the description and, secondly, at least one further known active compound from groups (2) to (27) listed in the description, which combinations are highly suitable for controlling animal pests such as insects and unwanted acarids and also phytopathogenic fungi.
Substituted imide derivatives
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, (2008/06/13)
The present invention relates to novel substituted imide derivatives of the general formula (I) in which R1 represents optionally substituted cycloalkyl, R2 represents optionally substituted alkyl or optionally substituted cycloalkyl, R3 represents alkyl, alkoxy, alkylthio, amino, alkylamino or dialkylamino and R4 represents cyano or nitro, and to processes for their preparation and to their use for controlling animal pests and as herbicides.