28232-30-6

Basic information

• Product Name: 2-(4-CHLOROPHENOXY)-5-NITROPYRIDINE
• Synonyms: 2-(4-CHLOROPHENOXY)-5-NITROPYRIDINE
• CAS NO: 28232-30-6
• Molecular Formula: C₁₁H₇ClN₂O₃
• Molecular Weight: 250.64
• Mol File: 28232-30-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 93 °C
• Boiling Point: 364.6°Cat760mmHg
• Flash Point: 174.3°C
• Appearance: /
• Density: 1.415g/cm³
• Vapor Pressure: 3.5E-05mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: 2-(4-CHLOROPHENOXY)-5-NITROPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-CHLOROPHENOXY)-5-NITROPYRIDINE(28232-30-6)
• EPA Substance Registry System: 2-(4-CHLOROPHENOXY)-5-NITROPYRIDINE(28232-30-6)

Safety Data

• Hazard Codes: T
• Statements: 25-43
• Safety Statements: 36/37-45
• Hazardous Substances Data: 28232-30-6(Hazardous Substances Data)

Usage

General Description

2-(4-chlorophenoxy)-5-nitropyridine is a chemical compound with the molecular formula C11H7ClN2O3. It is a yellow solid with a molecular weight of 244.64 g/mol. 2-(4-CHLOROPHENOXY)-5-NITROPYRIDINE is used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is also known for its application in the field of agrochemicals, especially as a building block for the development of herbicides and pesticides. 2-(4-chlorophenoxy)-5-nitropyridine is a potent and versatile compound that plays a crucial role in the production of various products in the pharmaceutical and agricultural industries.

InChI:InChI=1/C11H7ClN2O3/c12-8-1-4-10(5-2-8)17-11-6-3-9(7-13-11)14(15)16/h1-7H

Upstream product

• 4548-45-2 2-chloro-5-nitropyridine 
• 1193-00-6 sodium 4-chlorophenolate 
• 106-48-9 4-chloro-phenol 
• 1121-74-0 potassium 4-chlorophenoxide 

Downstream Products

• 75926-64-6 6-(4-chlorophenoxy)-3-aminopyridine 

Relevant articles and documents

Isothiazole compound and application thereof

The invention belongs to the field of agricultural fungicides and acaricides, and particularly relates to an isothiazole compound and an application thereof. The structural formula of the compound is as shown in the specification, and definitions of substituent group are indicated in instructions. The general compound has broad-spectrum bactericidal and insecticidal activity in the field of agriculture and excellent prevention and control effects on various germs such as corn rust diseases, rice blast, cucumber downy mildew and cucumber anthracnose. Particularly, the general compound has excellent prevention and treatment effects on the cucumber downy mildew and the cucumber anthracnose under low dosage. Besides, the partial compound has good acaricidal activity and can be used for preventing and treating tetranychus cinnabrinus and the like.

Kinetics of the reaction of 2-chloro-3-nitro- and 2-chloro-5-nitropyridines with aryloxide ions in methanol

The kinetics of the reaction of 2-chloro-3-nitropyridine (ortho-like) and 2-chloro-5-nitropyridine (para-like) with a series of aryloxide ions were studied in methanol at different temperatures. Plots of ΔH* versus ΔS* for both reactions gave good straight lines with isokinetic temperatures of 168 and 195°C. Good linear relationships were obtained from the plots of log k2 against σ° values with relatively large negative ρ values indicating the formation of Meisenheimer σ-complex intermediates. Plots of log k2 against pKa values gave good straight lines indicating that the reactions show an appreciable degree of bond formation in the transition state. An addition-elimination mechanism is suggested. Copyright