28907-18-8

Basic information

• Product Name: 4-Cyclohexene-1,2-dicarboxamide
• Synonyms: 4-Cyclohexene-1,2-dicarboxamide
• CAS NO: 28907-18-8
• Molecular Formula: C8H12N2O2
• Molecular Weight: 0
• Mol File: 28907-18-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Cyclohexene-1,2-dicarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Cyclohexene-1,2-dicarboxamide(28907-18-8)
• EPA Substance Registry System: 4-Cyclohexene-1,2-dicarboxamide(28907-18-8)

Safety Data

• Hazardous Substances Data: 28907-18-8(Hazardous Substances Data)

Upstream product

• 28907-19-9 (1R,2S)-Cyclohex-4-ene-1,2-dicarbonitrile 
• 88-98-2 cyclohex-4-ene-1,2-dicarboxylic acid 
• 1469-48-3 cis-1,2,3,6-Tetrahydrophthalimide 

Downstream Products

• 1469-49-4 cis-1,2,3,6-tetrahydrophthalamic acid 
• 189125-29-9 (1R,2S)-cis-2-aminocyclohex-4-enecarboxylic acid 
• 191803-49-3 C₇H₁₃NO 

Relevant articles and documents

Modification of the Enantioselectivity of Biocatalytic meso-Desymmetrization for Synthesis of Both Enantiomers of cis-1,2-Disubstituted Cyclohexane by Amidase Engineering

Both enantiomers of cis-1,2-disubstituted cyclohexane have been obtained enantioselectively through engineered amidase-catalyzed desymmetrization of meso carbocyclic 1,2-dicarboxamides under mild condition. Based on the enzyme-substrate binding model sugg

Corresponding amine nitrile and method of manufacturing thereof

The invention relates to a preparation method of nitrile. Compared with the prior art, the preparation method has the characteristics of obvious reduction of the usage amount of ammonia sources, low environmental pressure, low energy consumption, low production cost, high purity and yields of nitrile products, and the like, and can be used for obtaining nitrile with a more complex structure. The invention also relates to a method for preparing corresponding amine with nitrile.

Rhodococcus rhodochrous IFO 15564-mediated hydrolysis of alicyclic nitriles and amides: Stereoselectivity and use for kinetic resolution and asymmetrization

The stereocourse and the selectivity of the hydrolysis of alicyclic mono- and dinitriles and amides mediated by Rhodococcus rhodochrous IFO · 15564 has been examined. The stereochemistry of the substrates, as well as the nature of substituents and presence of double bonds in alicyclic rings greatly affected the rate of hydrolysis by nitrile hydratase and amidase. The rate difference between enantiomers or enantiotopic groups, in some cases, enabled kinetic resolution or asymmetrization. The highest enantioselectivity of amidase was observed in the hydrolysis of 5-benzoyloxy-3-cyclohexene-1- carboxamide (E>200), and both enantiomers of methyl 5-hydroxy-3-cyclohexene- 1-carboxylate thus became readily available.