28942-32-7

Basic information

• Product Name: Phenol, 4-(1-naphthalenylmethyl)-
• CAS NO: 28942-32-7
• Molecular Formula: C17H14O
• Molecular Weight: 234.298
• Mol File: 28942-32-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Phenol, 4-(1-naphthalenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-(1-naphthalenylmethyl)-(28942-32-7)
• EPA Substance Registry System: Phenol, 4-(1-naphthalenylmethyl)-(28942-32-7)

Safety Data

• Hazardous Substances Data: 28942-32-7(Hazardous Substances Data)

Upstream product

• 3163-27-7 2-(bromomethyl)naphthalene 
• 108-95-2 phenol 
• 6245-96-1 α-naphthylmethyl phenyl ether 
• 158833-25-1 naphthalen-1-ylmethyl phenyl carbonate 
• 86-52-2 1-Chloromethylnaphthalene 

Downstream Products

• 32891-88-6 (4-methoxyphenyl)(naphth-1-yl)methane 

Relevant articles and documents

Metal-Free C-O Bond Functionalization: Catalytic Intramolecular and Intermolecular Benzylation of Arenes

A catalytic, metal-free intramolecular rearrangement of benzyl phenyl ethers using nitrosonium salt as a catalyst is described. The optimized reaction conditions enabled a catalytic and metal-free Friedel-Crafts alkylation reaction with benzylic alcohols, producing water as the stoichiometric byproduct. A comprehensive scope (>50 examples) for both approaches and application in drug synthesis were demonstrated. Mechanistic studies suggest a Lewis acid-based mechanism for the metal-free Friedel-Crafts reaction.