293731-49-4

Basic information

• Product Name: benzyl 2-(4-fluorophenyl)ethanoate
• Synonyms: benzyl 2-(4-fluorophenyl)ethanoate
• CAS NO: 293731-49-4
• Molecular Weight: 244.265
• Mol File: 293731-49-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: benzyl 2-(4-fluorophenyl)ethanoate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 2-(4-fluorophenyl)ethanoate(293731-49-4)
• EPA Substance Registry System: benzyl 2-(4-fluorophenyl)ethanoate(293731-49-4)

Safety Data

• Hazardous Substances Data: 293731-49-4(Hazardous Substances Data)

Upstream product

• 702-11-4 4-fluoro-N,N-dimethylbenzylamine 
• 201230-82-2 carbon monoxide 
• 100-51-6 benzyl alcohol 
• 405-50-5 p-Fluorophenylacetic acid 
• 459-04-1 4-Fluorophenylacetyl chloride 
• 1090480-39-9 N-(benzyloxy)-2-(4-fluorophenyl)acetamide 
• 108-88-3 toluene 
• 100-39-0 benzyl bromide 

Downstream Products

• 512176-89-5 benzyl 2-benzoyl-2-(4-fluorophenyl)propanoate 
• 512176-77-1 benzyl 2-benzoyl-2-(4-fluorophenyl)ethanoate 
• 293731-51-8 (RS)-benzyl 2-(4-fluorophenyl)-3-phthalimidopropanoate 
• 293731-64-3 (αS,3'R)-4',4'-dimethyl-γ-butyrolacton-3'-yl 2-(4-fluorophenyl)-3-phthalimidopropanoate 
• 267001-10-5 (αR,3'R)-4',4'-dimethyl-γ-butyrolacton-3'-yl 2-(4-fluorophenyl)-3-phthalimidopropanoate 
• 293731-59-6 (RS)-3-phthalimido-2-(4-fluorophenyl)propanoic acid chloride 
• 293731-55-2 (RS)-2-(4-fluorophenyl)-3-phthalimidopropanoic acid 

Relevant articles and documents

Palladium-catalyzed carbonylation of benzylic ammonium salts to amides and esters: Via C-N bond activation

An efficient palladium-catalyzed carbonylation reaction of readily available quaternary ammonium salts with CO is reported for the first time to afford arylacetamides and arylacetic acid esters via benzylic C-N bond cleavage. This protocol features mild reaction conditions under atmospheric pressure of CO, a redox-neutral process without an additional oxidant, and a broad substrate scope for various kinds of amines, alcohols and phenols.

Palladium-catalyzed benzylation of carboxylic acids with toluene via benzylic C-H activation

Direct benzylation of carboxylic acids with toluene has been developed via palladium-catalyzed C-H acyloxylation under 1 atm of oxygen. This reaction demonstrates good functional group tolerance and high yields, providing a facile, atom-economic, and efficient method for the synthesis of benzyl esters.

Asymmetric synthesis of (S)-β2-homoarylglycines

The synthesis of racemic N-phthalyl β2-homoarylglycines 5 and their asymmetric transformation have been investigated. The key step is the stereoselective addition of the (R)-pantolactone to the corresponding prochiral ketene 7.