29843-62-7Relevant articles and documents
SELECTIVITY OF TETRAHYDROFURAN FORMATION FROM UNACTIVATED ALIPHATIC ALCOHOLS BY THE BROMINE-SILVER-SALT REACTION
Roscher, Nina Matheny,Shaffer, D. Kent
, p. 2643 - 2650 (2007/10/02)
Studies of the bromine-silver carbonate reaction with aliphatic alcohols in which intramolecular δ-H competition is possible are generally quite specific.Loss of a tertiary δ- hydrogen occurs preferentially from both tertiary and secondary aliphatic alcohols to yield the most highly substituted cyclic ether.For example, 2,5-dimethyl-2-octanol yields only 2,2,5-trimethyl-5-propyltetrahydrofuran as the cyclic ether product; 2-methyl-2-isopentyltetrahydrofuran is not detected.