30018-16-7 Usage
Description
[1-(Ethoxycarbonyl)ethyl]triphenylphosphonium bromide is a white to off-white powder that serves as an important raw material and intermediate in various chemical industries. It is commonly utilized in organic synthesis, pharmaceuticals, agrochemicals, and dyestuff due to its unique chemical properties and reactivity.
Uses
Used in Organic Synthesis:
[1-(Ethoxycarbonyl)ethyl]triphenylphosphonium bromide is used as a catalyst in the Suzuki reaction, a widely employed method for the formation of carbon-carbon bonds, particularly in the synthesis of biaryl compounds. Its application in this reaction enhances the efficiency and selectivity of the process, making it a valuable component in the field of organic chemistry.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, [1-(Ethoxycarbonyl)ethyl]triphenylphosphonium bromide is used as an organophosphine catalyst for various chemical reactions. Its ability to facilitate bond formation and transformation makes it a crucial component in the synthesis of complex pharmaceutical compounds, contributing to the development of new drugs and therapies.
Used in Agrochemicals:
[1-(Ethoxycarbonyl)ethyl]triphenylphosphonium bromide is used as a catalyst in the agrochemical industry, where it aids in the synthesis of various pesticides and other agricultural chemicals. Its application in this field helps improve the efficiency of chemical reactions, leading to the production of more effective and environmentally friendly agrochemicals.
Used in Dyestuff Industry:
In the dyestuff industry, [1-(Ethoxycarbonyl)ethyl]triphenylphosphonium bromide is used as a catalyst for the synthesis of various dyes and pigments. Its role in facilitating chemical reactions allows for the production of a wide range of colors and hues, contributing to the diversity and vibrancy of the dyestuff market.
Overall, [1-(Ethoxycarbonyl)ethyl]triphenylphosphonium bromide is a versatile and essential compound in the fields of organic synthesis, pharmaceuticals, agrochemicals, and dyestuff, playing a crucial role in the development and production of various products and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 30018-16-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,0,1 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 30018-16:
(7*3)+(6*0)+(5*0)+(4*1)+(3*8)+(2*1)+(1*6)=57
57 % 10 = 7
So 30018-16-7 is a valid CAS Registry Number.
InChI:InChI=1/C23H24O2P.BrH/c1-3-25-23(24)19(2)26(20-13-7-4-8-14-20,21-15-9-5-10-16-21)22-17-11-6-12-18-22;/h4-19H,3H2,1-2H3;1H/q+1;/p-1
30018-16-7Relevant articles and documents
A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS
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Paragraph 000275; 000276, (2021/03/02)
The present invention relates to the conjugation of a tubulysin analog compound to a cell-binding molecule with branched/side-chain linkers for having better delivery of the conjugate compound and targeted treatment of abnormal cells. It also relates to a branched-linkage method of conjugation of a tubulysin analog molecule to a cell-binding ligand, as well as methods of using the conjugate in targeted treatment of cancer, infection and autoimmune disease.
A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS
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Page/Page column 10; 164, (2019/07/17)
The present invention relates to the conjugation of a tubulysin analog compound to a cell-binding molecule with branched/side-chain linkers for having better delivery of the conjugate compound and targeted treatment of abnormal cells. It also relates to a branched-linkage method of conjugation of a tubulysin analog molecule to a cell-binding ligand, as well as methods of using the conjugate in targeted treatment of cancer, infection and autoimmune disease.
Close the ring to break the cycle: Tandem quinolone-alkyne-cyclisation gives access to tricyclic pyrrolo[1,2-: A] quinolin-5-ones with potent anti-protozoal activity
Szamosvári, Dávid,Sylvester, Kayla,Schmid, Philipp,Lu, Kuan-Yi,Derbyshire, Emily R.,B?ttcher, Thomas
supporting information, p. 7009 - 7012 (2019/06/20)
Expanding the chemical space of quinolones led to a tandem quinolone-alkyne-cyclisation reaction allowing chemoselective control of the synthesis of tricyclic pyrrolo[1,2-a]quinolin-5-ones. Importantly, we discovered anti-protozoal activity against Plasmodium and Toxoplasma with specific potency of one of the compounds against the liver stage of the malaria parasite in the nanomolar range.
