30186-41-5

Basic information

• Product Name: 1-(4-NITROPHENYL)-1H-PYRROLE-2-CARBALDEHYDE
• Synonyms: ART-CHEM-BB B006903;AKOS B006903;AKOS AUF01650;1-(4-NITROPHENYL)-1H-PYRROLE-2-CARBALDEHYDE;1-(4-NITROPHENYL)-1H-PYRROLE-2-CARBOXALDEHYDE;1-(4-nitrophenyl)-2-pyrrolecarboxaldehyde;1-(4-nitrophenyl)pyrrole-2-carbaldehyde
• CAS NO: 30186-41-5
• Molecular Formula: C₁₁H₈N₂O₃
• Molecular Weight: 216.19
• Mol File: 30186-41-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 166.5 °C
• Boiling Point: 398.6°Cat760mmHg
• Flash Point: 194.8°C
• Appearance: /
• Density: 1.3g/cm³
• Vapor Pressure: 1.46E-06mmHg at 25°C
• Refractive Index: 1.623
• PKA: -10.20±0.70(Predicted)
• CAS DataBase Reference: 1-(4-NITROPHENYL)-1H-PYRROLE-2-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-NITROPHENYL)-1H-PYRROLE-2-CARBALDEHYDE(30186-41-5)
• EPA Substance Registry System: 1-(4-NITROPHENYL)-1H-PYRROLE-2-CARBALDEHYDE(30186-41-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 30186-41-5(Hazardous Substances Data)

Usage

General Description

1-(4-Nitrophenyl)-1H-pyrrole-2-carbaldehyde is a chemical compound with the molecular formula C11H8N2O3. It is a derivative of pyrrole, which is a five-membered aromatic ring containing one nitrogen atom. The compound contains a nitro group (NO2) attached to the phenyl ring, giving it a yellow crystalline appearance. The carbaldehyde group (CHO) is attached to the pyrrole ring, making it an aldehyde compound. This chemical may be used in organic synthesis and research as a building block for the generation of various functionalized pyrrole derivatives and related compounds. Its functional groups make it suitable for use in a variety of applications in chemical and pharmaceutical industries.

InChI:InChI=1/C11H8N2O3/c14-8-11-2-1-7-12(11)9-3-5-10(6-4-9)13(15)16/h1-8H

Upstream product

• 98-01-1 furfural 
• 100-01-6 4-nitro-aniline 
• 1003-29-8 2-pyrrole aldehyde 
• 350-46-9 4-Fluoronitrobenzene 

Downstream Products

• 63751-48-4 8-[1-(4-nitro-phenyl)-pyrrol-2-ylmethylene]-imidazo[2,1-b]naphtho[2,1-d]thiazol-9-one 
• 43053-81-2 1-(4-nitrophenyl)-2-pyrrolecarbonitrile 
• 82766-06-1 4,5-dibromo-1-(4-nitrophenyl)-2-formylpyrrole 
• 82766-08-3 3,4-dibromo-1-(4-nitrophenyl)-2-formylpyrrole 
• 82766-07-2 1-(4-nitrophenyl)-4-bromo-2-formylpyrrole 
• 82766-05-0 1-(4-nitrophenyl)-5-bromo-2-formylpyrrole 
• 68414-86-8 1-(4-nitrophenyl)-Δ³-pyrrolin-2-one 
• 124475-62-3 1-(p-Nitrophenyl)-2-formylpyrrole s-cis-anti-oxime 
• 124475-61-2 1-(p-Nitrophenyl)-2-formylpyrrole s-trans-syn-oxime 
• 82552-86-1 1-(4-nitrophenyl)-1H-pyrrole-2-carboxylic acid 
• 90828-51-6 1-(p-Nitrophenyl)-3-formylpyrrole 
• 65833-16-1 3,4-dibromo-1-(4-nitrophenyl)-1H-pyrrole-2,5-dione 
• 4338-06-1 N-(4-nitrophenyl)maleimide 
• 122275-92-7 N-(4-{[1-[1-(4-Nitro-phenyl)-1H-pyrrol-2-yl]-meth-(E)-ylidene]-amino}-phenyl)-acetamide 

Relevant articles and documents

First hyperpolarizability orientation in asymmetric pyrrole-based polyene chromophores

Novel, asymmetrically shaped, pyrrole-based polyene chromophores were designed to obtain a large angle θ(μ,βmax) between the directions of the maximum first hyperpolarizability βmax and the dipole moment μ, by introducing an asymmetric core pyrrole into the π-conjugated polyene bridge of the chromophore. Asymmetric N-substituted pyrrolic nonlinear optical chromophores based on configurationally locked polyene (CLP) were synthesized and their first hyperpolarizabilities were theoretically determined using density functional theory (DFT). High asymmetry with an angle θ(μ,βmax) between the dipole moment μ and the main direction of the charge-transfer transition βmax of up to 48° was achieved.

Reactions of Stenhouse Salts. III Transformation Products Under Acidic and Basic Conditions

Mild acid treatment of alcoholic solutions of Stenhouse salts has been shown to yield a mixture of the corresponding N-arylpyrrole-2-carbaldehyde and the N-aryl-3-hydroxypyridinium salt.Treatment of alcoholic solutions of the Stenhouse salts with a variety of bases leads to 4-substituted 2-arylaminocyclopent-2-enones.

Research on substances with antiblastic activity. LIII. Synthesis and cytostatic and cytotoxic activity of amides of arylpyrrolcarboxylic acids

-