30765-95-8Relevant articles and documents
Electrochemical-mediated fixation of CO2: three-component synthesis of carbamate compounds from CO2, amines andN-alkenylsulfonamides
Liang, Ying,Pan, Ying-Ming,Tang, Hai-Tao,Xiong, Ting-Kai,Zhang, Min,Zhou, Xue-Qi
supporting information, p. 4328 - 4332 (2021/06/30)
An electrocatalyzed three-component cascade reaction of CO2, amines, andN-alkenylsulfonamides is developed, providing an environmentally friendly and efficient method of synthesizing a series of new carbamate compounds. This reaction meets the needs of green chemistry and promotes the participation of carbon dioxide in the three-component reaction by electro-oxidation. Pharmacological activity studies further prove that carbamate compounds have better activity than diamination by-products.
Directing-group-assisted markovnikov-selective hydrothiolation of styrenes with thiols by photoredox/cobalt catalysis
Xiao, Qian,Zhang, Hong,Li, Jing-Hong,Jian, Jing-Xin,Tong, Qing-Xiao,Zhong, Jian-Ji
supporting information, p. 3604 - 3609 (2021/05/10)
In contrast with the well-developed radical thiol-ene reaction to access anti-Markovnikov-type products, the research on the catalytic Markovnikov-selective hydrothiolation of alkenes is very restricted. Because of the catalyst poisoning of metal catalysts by organosulfur compounds, limited examples of transition-metal-catalyzed thiol-ene reactions have been reported. However, in this work, a directing-group-assisted hydrothiolation of styrenes with thiols by photoredox/cobalt catalysis is found to proceed smoothly to afford Markovnikov-type sulfides with excellent regioselectivity.
Pd-tBuONO Cocatalyzed Aerobic Indole Synthesis
Ning, Xiao-Shan,Liang, Xin,Hu, Kang-Fei,Yao, Chuan-Zhi,Qu, Jian-Ping,Kang, Yan-Biao
supporting information, p. 1590 - 1594 (2018/04/30)
A Pd-tBuONO co-catalyzed scalable and practical synthesis of indoles with molecular oxygen as terminal oxidant is developed. Either terminal or internal 2-vinylanilines could be smoothly converted to desired indoles under one general condition. This method has been evaluated in the large scale synthesis of indomethacin and a potential anti-breast cancer drug candidate 1. (Figure presented.).