3086-62-2

Basic information

• Product Name: 3,4,5-TRIMETHOXYBENZAMIDE
• Synonyms: 3,4,5-TRIMETHOXYBENZAMIDE;3,4,5-trimethoxy-benzamid;Benzamide, 3,4,5-trimethoxy-;TriMethoxybenzaMide;3,4,5-triMethoxybenzoicaMide;http://www.shshiji.coM/ProductInfo.aspxPID=11479
• CAS NO: 3086-62-2
• Molecular Formula: C₁₀H₁₃NO₄
• Molecular Weight: 211.21
• EINECS: 221-406-6
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Amides;Carbonyl Compounds;Organic Building Blocks
• Mol File: 3086-62-2.mol
• Article Data: 36

Chemical Properties

• Melting Point: 179-184 °C(lit.)
• Boiling Point: 350.89°C (rough estimate)
• Flash Point: 104.2 °C
• Appearance: /
• Density: 1.2545 (rough estimate)
• Vapor Pressure: 0.0051mmHg at 25°C
• Refractive Index: 1.5150 (estimate)
• PKA: 15.95±0.50(Predicted)
• BRN: 2697325
• CAS DataBase Reference: 3,4,5-TRIMETHOXYBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4,5-TRIMETHOXYBENZAMIDE(3086-62-2)
• EPA Substance Registry System: 3,4,5-TRIMETHOXYBENZAMIDE(3086-62-2)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 2
• RTECS: CV6125000
• TSCA: Yes
• Hazardous Substances Data: 3086-62-2(Hazardous Substances Data)

Usage

General Description

3,4,5-Trimethoxybenzamide is a chemical compound with the molecular formula C10H13NO4. It is an amide derivative of 3,4,5-trimethoxybenzoic acid, and its primary use is as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 3,4,5-Trimethoxybenzamide is also used in the production of dyes, pigments, and other specialty chemicals. It is a white to off-white crystalline powder with a melting point of 119-121°C and is soluble in organic solvents. 3,4,5-TRIMETHOXYBENZAMIDE is not known to have any significant commercial applications outside of the chemical and pharmaceutical industries.

InChI:InChI=1/C10H13NO4/c1-13-7-4-6(10(11)12)5-8(14-2)9(7)15-3/h4-5H,1-3H3,(H2,11,12)

Upstream product

• 4521-61-3 3,4,5-Trimethoxybenzoyl chloride 
• 618-73-5 3,4,5-trihydroxybenzamide 
• 77-78-1 dimethyl sulfate 
• 118-41-2 Eudesmic acid 
• 3840-31-1 (3,4,5-trimethoxyphenyl)methanol 
• 1885-35-4 3,4,5-trimethoxybenzonitrile 
• 39201-89-3 3,4,5-trimethoxybenzaldehyde oxime 
• 591-50-4 iodobenzene 
• 615-42-9 1,2-Diiodobenzene 
• 53560-33-1 3,4,5-trimethoxyphenylacetylene 
• 1136-86-3 methyl (3,4,5-trimethoxyphenyl) ketone 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 23346-82-9 2-bromo-3,4,5-trimethoxybenzoic acid 
• 49834-25-5 3,4,5-trimethoxy(N-tert-butylcarbamoyl)benzene 

Downstream Products

• 110554-71-7 bis-(3,4,5-trimethoxy-benzoyl)-amine 
• 52605-12-6 1,2-bis(3,4,5-tri-methoxyphenyl)ethane-1,2-dione 
• 102169-02-8 3,4,5,3',4',5'-hexamethoxy-deoxybenzoin 
• 55100-33-9 N-methyl-3,4,5-trimethoxybenzamide 
• 138-56-7 Trimethobenzamide 
• 3940-84-9 N-benzyl-3,4,5-trimethoxybenzamide 
• 40915-27-3 (3,4,5-trimethoxybenzoylamino)acetic acid 
• 681277-36-1 5-Chloromethyl-4-methyl-2-(3,4,5-trimethoxy-phenyl)thiazole 
• 681277-35-0 5-Hydroxymethyl-4-methyl-2-(3,4,5-trimethoxy-phenyl)thiazole 
• 77853-50-0 2-(3,4,5-trimethoxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester 
• 1449485-73-7 3,4,5-trimethoxy-2-(3-(trifluoromethyl)benzyl)benzamide 
• 1385626-32-3 N-(1H-indol-5-yl)-3,4,5-trimethoxybenzamide 

Relevant articles and documents

Photophysical properties and photoreduction of N-acetyl- and N-benzoylphthalimides

The photophysical properties and photoreduction of N-acetylphthalimide (AcP) and N-benzoylphthalimide (BzP), N-3,4,5-trimethoxybenzoylphthalimide (trimethoxyBzP) and N-4-nitrobenzoylphthalimide (nitroBzP) were studied by steady-state and transient techniques. Radicals and their precursor triplet states were detected by flash photolysis. The triplet state properties of AcP and BzP were characterized. In contrast, no triplet absorption was observed with ns-detection for trimethoxyBzP and nitroBzP. Specific products are formed upon electron transfer from triethylamine to the photoexcited acylphthalimides. In addition, H-atom transfer from 2-propanol or other alcohols to the triplet state takes place. The properties of several radical intermediates involved in photoreduction of the acylphthalimides as well as some structure-function relationships are described.

Nano-construction of CuO nanorods decorated with g-C3N4 nanosheets (CuO/g-C3N4-NS) as a superb colloidal nanocatalyst for liquid phase C[sbnd]H conversion of aldehydes to amides

Herein, we describe an intelligent strategy to fabricate nanosheets of graphitic carbon nitride (g-C3N4) decorated with nanorods copper oxide (CuO NRs). Then, the catalytic activity of CuONRs/g-C3N4-NS was developed for the synthesis of primary amides in water. The morphology of CuO and its synergetics effect with nanosheets g-C3N4 a major role in the yield of products. Furthermore, hydroxylamine hydrochloride (NH2OH·HCl) due to availability and affordability was used as a suitable substitute for ammonia source. The findings demonstrate that this layer nanostructure is a superb catalyst for converting various derivatives of aldehyde to their corresponding amides. The current protocol can be useful criterion in the synthesis and stabilization of metal oxides and provides new insight in organic transformation.

Base promoted peroxide systems for the efficient synthesis of nitroarenes and benzamides

A useful and efficient approach for the synthesis of nitroarenes from several aromatic amines (including heterocycles) using peroxide and base has been developed. This oxidative reaction is very easy to handle and afforded the products in good yields. Formation of benzamides from benzylamine was also successfully carried out with this metal-free catalytic system in good to excellent yields.