32084-59-6

Basic information

• Product Name: 6-Bromoquinazolin-4-ol
• Synonyms: 6-Bromoquinazolin-4(3H)-one;6-Bromo-3,4-dihydro-4-oxoquinazoline 98%;6-Bromo-4-hydroxyquinazoline;6-bromo-4-quinazolinone;6-Bromoquinazolin-4-ol;6-bromo-4(3h)-quinazolinone;6-Bromoquinazolin-4(3H)-one 98%;6-bromoquinazolin-4(3H)-one(SALTDATA: FREE)
• CAS NO: 32084-59-6
• Molecular Formula: C₈H₅BrN₂O
• Molecular Weight: 225.04
• Product Categories: blocks;Heterocycles;Quinolines
• Mol File: 32084-59-6.mol
• Article Data: 86

Chemical Properties

• Melting Point: 131-132 °C
• Boiling Point: 374.2 °C at 760 mmHg
• Flash Point: 180.1 °C
• Appearance: /
• Density: 1.82 g/cm³
• Vapor Pressure: 8.51E-06mmHg at 25°C
• Refractive Index: 1.72
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 1.05±0.20(Predicted)
• CAS DataBase Reference: 6-Bromoquinazolin-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Bromoquinazolin-4-ol(32084-59-6)
• EPA Substance Registry System: 6-Bromoquinazolin-4-ol(32084-59-6)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• Hazardous Substances Data: 32084-59-6(Hazardous Substances Data)

Usage

Chemical Properties

White powder

InChI:InChI=1/C8H5BrN2O/c9-5-1-2-7-6(3-5)8(12)11-4-10-7/h1-4H,(H,10,11,12)

Upstream product

• 77287-34-4 formamide 
• 5794-88-7 5-Bromo-2-aminobenzoic acid 
• 20353-93-9 Gold's reagent 
• 39263-32-6 2-amino-5-bromobenzonitrile 
• 68-12-2 N,N-dimethyl-formamide 
• 87-48-9 5-Bromo-1H-indole-2,3-dione 
• 4692-98-2 5-bromoisatoic anhydride 
• 38267-96-8 6-bromo-4-chloroquinozoline 
• 50-00-0 formaldehyd 
• 16313-66-9 5-bromoanthranilamide 
• 52727-57-8 5-bromo-2-aminobenzoic acid methyl ester 
• 118-92-3 anthranilic acid 
• 463-52-5 formamidine 
• 3473-63-0 formamidine acetic acid 

Downstream Products

• 38267-96-8 6-bromo-4-chloroquinozoline 
• 75341-91-2 6-Bromo-3-(p-tolylamino-methyl)-3H-quinazolin-4-one 
• 75341-92-3 6-Bromo-3-[(4-chloro-phenylamino)-methyl]-3H-quinazolin-4-one 
• 75341-95-6 6-Bromo-3-[(4-methoxy-phenylamino)-methyl]-3H-quinazolin-4-one 
• 75341-90-1 6-Bromo-3-phenylaminomethyl-3H-quinazolin-4-one 
• 75341-94-5 6-Bromo-3-[(4-ethoxy-phenylamino)-methyl]-3H-quinazolin-4-one 
• 75341-93-4 4-[(6-Bromo-4-oxo-4H-quinazolin-3-ylmethyl)-amino]-benzoic acid ethyl ester 
• 75341-96-7 6-Bromo-3-[(4-bromo-phenylamino)-methyl]-3H-quinazolin-4-one 
• 49681-96-1 6-Bromo-2-mercapto-3,4-dihydrochinazolin-4-on 
• 677298-22-5 6-(2-chloro-6-methoxyphenyl)-3H-quinazolin-4-one 
• 677298-23-6 6-(2,4,6-trimethylphenyl)-3H-quinazolin-4-one 
• 1627942-07-7 6-bromo-3-(3-methyl-1H-indol-2-yl)-4a,8a-dihydro-3H-quinazolin-4-one 
• 1005010-01-4 4-chloro-6-(3,4-dimethoxy-phenyl)-quinazoline 
• 944549-41-1 N-[3-chloro-4-[(3-fluorobenzyl)oxy]phenyl]-6-bromo-quinazolin-4-amine 

Relevant articles and documents

Design and synthesis of novel 6-aryl substituted 4-anilinequinazoline derivatives as potential PI3Kδ inhibitors

In this study, a series of new 6-aryl substituted 4-anilinequinazolines was designed and synthesized as PI3Kδ inhibitors based on our reported chemical structures. The preliminary structure-activity relationship (SAR) was established, and compounds 13h an

Photo-Triggered Self-Induced Homolytic Dechlorinative Sulfonylation/Cyclization of Unactivated Alkenes: Synthesis of Quinazolinones Containing a Sulfonyl Group

A self-photocatalyzed sulfonylation/cyclization of quinazolinones containing unactivated alkenes with various sulfonyl chlorides was developed. The protocol provides access to sulfonyl radicals via energy transfer from the quinazolinone skeleton to the sulfonyl chloride. Notably, the transformations proceeded without any external photocatalysts, additives, or oxidants, providing an alternative method for fabricating sulfonylated compounds.

Visible-Light Photosynthesis of CHF2/CClF2/CBrF2-Substituted Ring-fused Quinazolinones in Dimethyl Carbonate

With eco-friendly and sustainable CO2-derived dimethyl carbonate as the sole solvent, the visible-light-induced cascade radical reactions have been established as a green and efficient tool for constructing various CHF2/CClF2/CBrF2-substituted ring-fused quinazolinones.