32418-62-5

Basic information

• Product Name: ethyl 2-morpholin-4-ylpropanoate
• Synonyms: ethyl 2-morpholin-4-ylpropanoate;2-morpholinopropanoic acid ethyl ester;2-morpholinopropionic acid ethyl ester;ethyl 2-morpholinopropanoate
• CAS NO: 32418-62-5
• Molecular Formula: C₉H₁₇NO₃
• Molecular Weight: 187.24
• Mol File: 32418-62-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 91-92 °C(Press: 4.5 Torr)
• Appearance: /
• Density: 1.056±0.06 g/cm3(Predicted)
• PKA: 5.14±0.10(Predicted)
• CAS DataBase Reference: ethyl 2-morpholin-4-ylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-morpholin-4-ylpropanoate(32418-62-5)
• EPA Substance Registry System: ethyl 2-morpholin-4-ylpropanoate(32418-62-5)

Safety Data

• Hazardous Substances Data: 32418-62-5(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 535-11-5 Ethyl 2-bromopropionate 
• 6111-99-5 ethyl diazoalaninate 

Downstream Products

• 32418-56-7 4-(1-[1,3,4]oxadiazol-2-yl-ethyl)-morpholine 
• 32418-66-9 2-Morpholinopropionsaeurehydrazid 

Relevant articles and documents

1,2-NAPHTHOQUINONE DERIVATIVE AND METHOD FOR PREPARING SAME

Disclosed are a compound represented by Formula (1), or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, tautomer, enantiomer, or pharmaceutically acceptable diastereomer thereof, a method of preparing the same, and a pharmaceutical composition, which have effects for treatment or prevention of metabolic syndromes, comprising the same: wherein R1to R6, X1 to X4, and n are the same as defined in Claim 1.

α-amino acid phenolic ester derivatives: Novel water-soluble general anesthetic agents which allosterically modulate gabaa receptors

In the search for a novel water-soluble general anesthetic agent the activity of an α-amino acid phenolic ester lead, identified from patent literature, was markedly improved. In addition to improving in vivo activity in mice, good in vitro activity at GABAA receptors was also conferred. Within the series of compounds good enantioselectivity for both in vitro and in vivo activity was found, supporting a protein-mediated mechanism of action for anesthesia involving allosteric modulation of GABAA receptors. α-Amino acid phenolic ester 19, as the hydrobromide salt Org 25435, was selected for clinical evaluation since it retained the best overall anesthetic profile coupled with improved stability and water solubility. In the clinic it proved to be an effective intravenous anesthetic in man with rapid onset of and recovery from anesthesia at doses of 3 and 4 mg/kg.

NEW RENIN-INHIBITORY OLIGOPEPTIDES, THEIR PREPARATION AND THEIR USE

Oligopeptides of formula (I): STR1 where R 1-R 5 are various organic groups, and A represents a group of formula--NH--or--(CH 2) n--, in which n represents an integer of from 1 to 3, have renin-inhibitory activity and are particularly suitable for oral administration. They may be prepared by condensing their component amino acids or lower oligopeptides using conventional peptide synthesis reactions.