3257-18-9

Basic information

• Product Name: Z-CYS(BZL)-OH
• Synonyms: Z-S-Bzl-L-Cys-OH;N-Cbz-S-benzyl-L-cysteine Cbz-Cys(Bzl)-OH;N-Cbz-S-(phenylMethyl)-L-cysteine;(R)-2-(((Benzyloxy)carbonyl)aMino)-3-(benzylthio)propanoic acid;Cbz-L-Cys(Bzl)-OH;N-Carbobenzoxy-S-benzyl-L-cysteine;Z-(S)-2-amino-3-(S-benzylthio)propanoic acid;Z-S-benzyl-L-cysteine≥ 99% (HPLC)
• CAS NO: 3257-18-9
• Molecular Formula: C₁₈H₁₉NO₄S
• Molecular Weight: 345.41
• EINECS: 221-855-8
• Product Categories: Amino Acid Derivatives;Cysteine [Cys, C]
• Mol File: 3257-18-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 96.0 to 100.0 °C
• Boiling Point: 560.6 °C at 760mmHg
• Flash Point: 292.9 °C
• Appearance: /
• Density: 1.278 g/cm³
• Vapor Pressure: 2.09E-13mmHg at 25°C
• Refractive Index: 1.61
• Storage Temp.: 2-8°C
• Solubility: Acetone (Sparingly), Chloroform (Slightly), DMSO (Slightly)
• CAS DataBase Reference: Z-CYS(BZL)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: Z-CYS(BZL)-OH(3257-18-9)
• EPA Substance Registry System: Z-CYS(BZL)-OH(3257-18-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 3257-18-9(Hazardous Substances Data)

Usage

Chemical Properties

White crystalline powder

InChI:InChI=1/C18H19NO4S/c20-17(21)16(13-24-12-15-9-5-2-6-10-15)19-18(22)23-11-14-7-3-1-4-8-14/h1-10,16H,11-13H2,(H,19,22)(H,20,21)

Upstream product

• 501-53-1 benzyl chloroformate 
• 16741-80-3 S-benzyl-L-cysteine methyl ester hydrochloride 
• 100-39-0 benzyl bromide 
• 96289-13-3 N-benzyloxycarbonyl-L-cysteine 
• 94311-65-6 Z-S(benzyl)-Cys-OMe 
• 3401-37-4 S-benzyl-N-carbobenzoxy-L-cysteine p-nitrophenyl ester 
• 3054-01-1 S-benzyl-L-cysteine 

Downstream Products

• 94311-65-6 Z-S(benzyl)-Cys-OMe 
• 3401-37-4 S-benzyl-N-carbobenzoxy-L-cysteine p-nitrophenyl ester 
• 16948-25-7 N-(S-benzyl-N-benzyloxycarbonyl-L-cysteinyl)-L-leucine ethyl ester 
• 65882-88-4 N²-(S-benzyl-N-benzyloxycarbonyl-L-cysteinyl)-L-asparagine 
• 75666-30-7 N-benzyloxycarbonyl-S-benzylcysteinyl-glycyl-glycine ethyl ester 
• 7625-12-9 N-(S-benzyl-N-benzyloxycarbonyl-L-cysteinyl)-L-phenylalanine methyl ester 
• 19519-00-7 N-(S-benzyl-N-benzyloxycarbonyl-L-cysteinyl)-L-tyrosine methyl ester 
• 21679-94-7 N-(S-benzyl-N-benzyloxycarbonyl-L-cysteinyl)-L-alanine methyl ester 
• 3695-79-2 Z-(Bzl)-L-Cys-Gly-OEt 
• 119681-42-4 S-benzyl-N-(S-benzyl-N-benzyloxycarbonyl-L-cysteinyl)-L-cysteine ethyl ester 
• 119697-68-6 S-benzyl-N-(S-benzyl-N-benzyloxycarbonyl-L-cysteinyl)-D-cysteine ethyl ester 
• 116928-49-5 S-benzyl-N-(S-benzyl-N-benzyloxycarbonyl-L-cysteinyl)-L-cysteine benzyl ester 
• 22911-82-6 S-benzilic-L-cysteic-NCA 
• 51220-78-1 (2S)-1-[(2S)-[(benzyloxy)carbonyl]-2-amino-3-(benzylthio)propanoyl]tetrahydro-1H-pyrrole-2-carboxylic acid 

Relevant articles and documents

Peptide Synthesis in Aqueous Solution. V. Properties and Reactivities of (p-Hydroxyphenyl)benzylmethylsulfonium Salts for Direct Benzyl Esterification of N-Acylpeptides

Some (p-hydroxyphenyl)benzylmethylsulfonium salts were prepared. These compounds generated a benzyl cation and converted not only N-acylamino acids but also N-acylpeptides into their corresponding benzyl esters without causing the racemization.

INTRAMOLECULAR CATALYTIC MECHANISMS INVOLVED IN THE ALKALINE HYDROLYSIS OF p-NITROPHENYL ESTERS OF α-CARBOBENZOXY AMINO ACIDS

A study on the alkaline hydrolysis of p-nitrophenyl esters of α-carbobenzoxy amino acids, in the presence and absence of free amino acids as catalysts, are reported.The effect of free amino acids represents an interesting model for the study of the cataly