3337-70-0Relevant articles and documents
Rapid and straightforward transesterification of sulfonyl carbamates
Isaksson, Rebecka,Kumpi?a, Ilze,Larhed, Mats,Wannberg, Johan
supporting information, p. 1476 - 1478 (2016/03/12)
A fast and convenient method for the alkoxy exchange of sulfonyl carbamates by simply heating in a chosen alkyl alcohol is described. No catalysts or additives are required. Microwave heating at 100-120 °C for 20-60 min resulted in good to excellent yields (53-93%) of alkyl (arylsulfonyl)carbamates where the alkyl part originates from the alcohol solvent. The developed protocol was applied to the synthesis of an angiotensin II type 2 receptor (AT2R) ligand.