3412-44-0

Basic information

• Product Name: 1,3-Diphenylpropene
• Synonyms: 1,3-Diphenyl-1-propene;1,3-Diphenylpropene;[(E)-3-phenylprop-1-enyl]benzene
• CAS NO: 3412-44-0
• Molecular Formula: C₁₅H₁₄
• Molecular Weight: 194.27166
• Mol File: 3412-44-0.mol
• Article Data: 299

Chemical Properties

• Boiling Point: 304.3°Cat760mmHg
• Flash Point: 141.4°C
• Appearance: /
• Density: 1.016g/cm³
• CAS DataBase Reference: 1,3-Diphenylpropene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Diphenylpropene(3412-44-0)
• EPA Substance Registry System: 1,3-Diphenylpropene(3412-44-0)

Safety Data

• Hazardous Substances Data: 3412-44-0(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 21, p. 27, 1980 DOI: 10.1016/S0040-4039(00)93615-3The Journal of Organic Chemistry, 31, p. 396, 1966 DOI: 10.1021/jo01340a012

Upstream product

• 22379-62-0 potassium benzyloxide 
• 122-78-1 phenylacetaldehyde 
• 1083-30-3 dihydrochalcone 
• 864078-99-9 C₃₁H₃₆N₃P 
• 16721-45-2 triphenyl(phenylmethylene)phosphorane 
• 100-52-7 benzaldehyde 
• 103-63-9 1-phenyl-2-bromoethane 
• 4392-24-9 Cinnamyl bromide 
• 95576-66-2 phenyltriethoxytitanium 
• 105-58-8 Diethyl carbonate 
• 5381-92-0 1,3-diphenylpropan-2-ol 
• 3536-29-6 2,3-diphenyl-1-propanol 
• 103-26-4 Methyl cinnamate 
• 66680-87-3 (E)-1-phenyl-(2-tributylstannyl)ethene 

Downstream Products

• 170277-50-6 2-benzyl-3-phenyloxirane 
• 56363-42-9 1,2-dibromo-1,3-diphenyl-propane 
• 1081-75-0 1,3-diphenylpropane 
• 3178-24-3 1,1'-(1,3-propanediyl)biscyclohexane 
• 36199-57-2 (E)-2,4-diphenylbut-3-enoic Acid 
• 103-82-2 phenylacetic acid 
• 100-52-7 benzaldehyde 
• 65-85-0 benzoic acid 
• 2294-90-8 1,3-diphenyl-2-propene-1-carboxylic acid 
• 5381-80-6 rac-(1R,2R)-1,3-diphenylpropane-1,2-diol 
• 56363-42-9 C₁₅H₁₄Br₂ 
• 116118-10-6 1,3-diphenyl-1,3-dimethoxy-2-phenylselenenyl propane 
• 116117-95-4 1,3-diphenyl-1-methoxy-2-phenylselenenyl propane 
• 116118-07-1 1,3-diphenyl-1-methoxy-2-chloro propane, erythro 

Relevant articles and documents

Nickel-Catalyzed C-Br/C-H Bis-phenylation of Methyl 4-Bromocrotonate: A Stereoselective Entry to Methyl (E)-3,4-Diphenylbut-2-enoate

A method for C-Br/C-H bis-phenylation of methyl 4-bromocrotonate via nickel-catalyzed cross-coupling reaction has been developed. This protocol involves commercially available catalyst components and furnishes a suitable doubly phenylated building block.

Vinylation of Benzylic Amines via C-N Bond Functionalization of Benzylic Pyridinium Salts

Cross-couplings of benzylic pyridinium salts and vinylboronic acids or esters have been developed. Via benzylic pyridinium intermediates, benzylic amines can be engaged in these cross-couplings through C-N bond functionalization. This method boasts mild reaction conditions and excellent tolerance for heteroaryl substituents and a range of functional groups.

Palladacycle-Catalyzed Regioselective Heck Reaction Using Diaryliodonium Triflates and Aryl Iodides

We describe a P-containing palladacycle-catalyzed regioselective Heck reaction of 2,3-dihydrofuran with diaryliodonium salts and aryl iodides to afford 2-aryl-2,5-dihydrofurans and 2-aryl-2,3-dihydrofurans, respectively, in good yields. Mechanistic studie

Nickel-Catalyzed Electrochemical C(sp3)?C(sp2) Cross-Coupling Reactions of Benzyl Trifluoroborate and Organic Halides**

Reported here is the redox neutral electrochemical C(sp2)?C(sp3) cross-coupling reaction of bench-stable aryl halides or β-bromostyrene (electrophiles) and benzylic trifluoroborates (nucleophiles) using nonprecious, bench-stable NiCl2?glyme/polypyridine catalysts in an undivided cell configuration under ambient conditions. The broad reaction scope and good yields of the Ni-catalyzed electrochemical coupling reactions were confirmed by 50 examples of aryl/β-styrenyl chloride/bromide and benzylic trifluoroborates. Potential applications were demonstrated by electrosynthesis and late-stage functionalization of pharmaceuticals and natural amino acid modification, and three reactions were run on gram-scale in a flow-cell electrolyzer. The electrochemical C?C cross-coupling reactions proceed through an unconventional radical transmetalation mechanism. This method is highly productive and expected to find wide-spread applications in organic synthesis.