341529-18-8 Usage
General Description
1-(1,1-Difluoro-1-cyclohexanol-1-yl-methyl)-2-phenylimidazole is a chemical compound consisting of a cyclohexanol group, a phenylimidazole group, and two fluorine atoms. It is often used in pharmaceutical and medicinal research due to its potential as a therapeutic agent or as a precursor to other biologically active compounds. The presence of the fluorine atoms enhances the compound's stability and can also modify its reactivity and selectivity. 1-(1,1-DIFLUORO-1-CYCLOHEXANOL-1-YL-METHYL)-2-PHENYLIMIDAZOLE may also have potential applications in the field of organic synthesis and material science due to its unique structure and properties. Further research and development may reveal additional uses for this chemical compound.
Check Digit Verification of cas no
The CAS Registry Mumber 341529-18-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,1,5,2 and 9 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 341529-18:
(8*3)+(7*4)+(6*1)+(5*5)+(4*2)+(3*9)+(2*1)+(1*8)=128
128 % 10 = 8
So 341529-18-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H18F2N2O/c17-16(18,15(21)9-5-2-6-10-15)20-12-11-19-14(20)13-7-3-1-4-8-13/h1,3-4,7-8,11-12,21H,2,5-6,9-10H2
341529-18-8Relevant articles and documents
Heteroaryl-N-difluoromethyltrimethylsilanes - Versatile sources of heteroaryl-N-difluoromethyl anions in reactions with carbonyl compounds
Bissky,Staninets,Kolomeitsev,R?schenthaler
, p. 374 - 378 (2007/10/03)
An efficient procedure for synthesizing heteroaryl-N-difluoromethyltrimethylsilanes - new nucleophilic difluoromethylene synthons - from easily available N-bromodifluoromethylated heterocycles, chlorotrimethylsilane and aluminium powder in triglyme or N-methylpyrrolidinone on a preparative scale in 71-75% isolated yield is described. Heteroaryl-N-difluoromethyltrimethylsilanes and benzaldehyde react under fluoride ion catalysis to give 1-(1,1-difluor-2-hydroxy-2-phenyl-ethyl)heteroaryls, whereas for anionic heteroaryl-N-difluoromethylation of cyclohexanone a stoichiometrical mixture of heteroaryl-N-difluoromethyltrimethylsilanes and tetramethylammonium fluoride has to be used.
