34387-64-9

Basic information

• Product Name: triphenyl(phenylethynyl)phosphonium
• CAS NO: 34387-64-9
• Molecular Formula: Br*C₂₆H₂₀P
• Molecular Weight: 363.4102
• Mol File: 34387-64-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: triphenyl(phenylethynyl)phosphonium(CAS DataBase Reference)
• NIST Chemistry Reference: triphenyl(phenylethynyl)phosphonium(34387-64-9)
• EPA Substance Registry System: triphenyl(phenylethynyl)phosphonium(34387-64-9)

Safety Data

• Hazardous Substances Data: 34387-64-9(Hazardous Substances Data)

Upstream product

• 20913-05-7 (Benzoylmethylene)triphenylphosphorane 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 603-35-0 triphenylphosphine 

Downstream Products

• 130281-63-9 [3-Methyl-2-phenyl-1-(triphenyl-λ⁵-phosphanylidene)-but-2-enyl]-triphenyl-phosphonium; bromide 
• 107299-96-7 (2,7-diphenyl-6-methyl-3,4-diaza-1,4,6-heptatrien-1-yl)-triphenylphosphonium bromide 
• 107299-97-8 (2,7-diphenyl-6-methyl-3,4-diaza-2,4,6-heptatrienylidene)triphenylphosphorane 
• 107300-06-1 6-Methyl-2,4,4,5-tetraphenyl-4,5-dihydro-pyrazolo[1,5-a]pyridine 
• 107300-09-4 6-Methyl-2,5-diphenyl-4,5-dihydro-pyrazolo[1,5-a]pyridine 
• 791-28-6 Triphenylphosphine oxide 
• 106547-04-0 triphenyl[2-phenyl-2-piperidinovinyl]phosphonium bromide 
• 215797-78-7 ethyl 1-phenyl-2-triphenylphosphoniovinylphosphonate 
• 130281-62-8 [(E)-2,3-Diphenyl-1-(triphenyl-λ⁵-phosphanylidene)-allyl]-triphenyl-phosphonium; bromide 

Relevant articles and documents

HSP70 INHIBITORS AND METHODS OF USING SAME

The disclosure provides compounds, and compositions comprising such compounds, that can be used to treat cancer, especially colorectal cancer (CRC). In certain embodiments, the compounds of the disclosure inhibit HSP70. In other embodiments, the compounds of the disclosure promote or increase immune cell recruitment to a cancer. In yet other embodiments, the compounds of the disclosure promote or increase immune cell infiltration in a cancer.

Ethynylphosphonium Salts, 2. A New Method for the Preparation of Ethynyltriphenylphosphonium Salts

The reaction between substituted (benzoylmethylene)- and (carbamoylmethylene)triphenylphosphoranes and the adduct of bromine to triphenylphosphane in the presence of triethylamine gives rise to the formation of (phenylethynyl)- resp. (aminoethynyl)triphen