34566-29-5Relevant articles and documents
Mechanistic studies on a dipeptide-promoted asymmetric cyclopropanation of unfunctionalized olefins
Long, Jiang,Xu, Liang,Du, Haifeng,Li, Kai,Shi, Yian
supporting information; experimental part, p. 5226 - 5229 (2010/02/28)
This paper describes mechanistic studies on a dipeptide-promoted asymmetric cyclopropanation system for unfunctionalized olefins. Zinc species generated from the deprotonation of the N-H of the dipeptide ligand have been investigated by NMR and X-ray stru
A Novel Class of Tunable Zinc Reagents (RXZnCH2Y) for Efficient Cyclopropanation of Olefins
Lorenz, Jon C.,Long, Jiang,Yang, Zhiqiang,Xue, Song,Xie, Yinong,Shi, Yian
, p. 327 - 334 (2007/10/03)
A class of zinc reagents (RXZnCH2Y) generated with an appropriate organozinc is very effective for the cyclopropanation of olefins. The reactivity and selectivity of these reagents can be regulated by tuning the electronic and steric nature of the RX group on Zn. A reasonable level of enantioselectivity was obtained for the cyclopropanation of unfunctionalized olefins when a chiral (iodomethyl)zinc species was used, providing a valuable approach for the asymmetric cyclopropanation of unfunctionalized olefins.