3470-35-7

Basic information

• Product Name: 4,4-dichloro-3-phenylcyclobut-2-en-1-one
• Synonyms: 2-Cyclobuten-1-one, 4,4-dichloro-3-phenyl-
• CAS NO: 3470-35-7
• Molecular Formula: C₁₀H₆Cl₂O
• Molecular Weight: 213.06
• Mol File: 3470-35-7.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 274.7°C at 760 mmHg
• Flash Point: 114.1°C
• Density: 1.41g/cm³
• Vapor Pressure: 0.00532mmHg at 25°C
• Refractive Index: 1.615
• CAS DataBase Reference: 4,4-dichloro-3-phenylcyclobut-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-dichloro-3-phenylcyclobut-2-en-1-one(3470-35-7)
• EPA Substance Registry System: 4,4-dichloro-3-phenylcyclobut-2-en-1-one(3470-35-7)

Safety Data

• Hazardous Substances Data: 3470-35-7(Hazardous Substances Data)

Upstream product

• 536-74-3 phenylacetylene 
• 1536-58-9 3,6-Dibromo-1-(4,4-dichloro-3,3-difluoro-cyclobut-1-enyl)-cyclohexene 
• 2713-84-0 4,4-dichloro-1-cyclohex-1-enyl-3,3-difluoro-cyclobutene 
• 931-49-7 1-ethenylcyclohexene 
• 76-02-8 trifluoroacetyl chloride 
• 340-01-2 4,4-dichloro-3,3-difluoro-1-phenyl-cyclobutene 

Downstream Products

• 103505-50-6 4,4-dichloro-3-phenyl-but-3-enoic acid 
• 109384-90-9 (2S,3R)-2-(2,2-Dichloro-1-phenyl-vinyl)-3-phenyl-cyclobutanone 
• 109384-99-8 (E)-4,4-Dichloro-3-phenyl-but-2-enoic acid allylamide 
• 109384-98-7 N-allyl-3-phenyl-4,4-dichloro-3-butenamide 
• 109384-91-0 cis-2-(2',2'-dichloro-1'-phenylvinyl)-3-methyl-3-vinylcyclobutanone 
• 109384-91-0 trans-2-(2',2'-dichloro-1'-phenylvinyl)-3-methyl-3-vinylcyclobutanone 
• 3947-97-5 3-phenyl-3-cyclobutene-1,2-dione 
• 475634-06-1 3,3-dichloro-2-phenyl-5,8-dioxa-spiro[3.4]oct-1-ene 
• 943921-11-7 methyl 3-phenylcyclobut-2-enyl carbonate 
• 943921-13-9 C₁₂H₁₂O₃ 
• 90843-07-5 3-phenyl-2-cyclobuten-1-ol 
• 103647-10-5 4-Methoxy-3-phenyl-2-butenoic acid lactone 
• 109384-90-9 (2S,3S)-2-(2,2-Dichloro-1-phenyl-vinyl)-3-phenyl-cyclobutanone 

Relevant articles and documents

-Cycloaddition Reaction of Sulfilimines with Cyclobutenones: Access to Benzazepinones

A catalyst-free [4+3]-cycloaddition reaction of N-aryl sulfilimines with cyclobutenones is described, which provides a straightforward protocol for synthesizing 1,5-dihydro-2H-benzo[b]azepin-2-ones under mild reaction conditions. This reaction features a

Enantioselective Synthesis of 4-Hydroxy-dihydrocoumarins via Catalytic Ring Opening/Cycloaddition of Cyclobutenones

A highly diastereo- and enantioselective ring-opening/cycloaddition reaction of cyclobutenones with 2-hydroxyacetophenones or salicylaldehyde was achieved by employing a chiral N,N′-dioxide-scandium(III) complex as the catalyst. It provided various 3-phen

Regiodivergent cyclobutanone cleavage: Switching selectivity with different Lewis acids

The exploitation of strain release in small rings as driving force to enable complex transformations is a powerful synthetic tool. Among them, cyclobutanones are particularly versatile substrates that can be elaborated in a wide variety of structurally diverse building blocks. Herein, Lewis acid catalyzed rearrangement reactions are presented that provide selective access to two structurally distinct polycyclic scaffolds, that is, indenylacetic acid derivatives and benzoxabicyclo[3.2.1]octan-3-ones. The choice of the Lewis acid fully controls the reaction pathway and the regioselectivity of the cyclobutanone C-C bond cleavage site.