352276-27-8

Basic information

• Product Name: 2-Butanone, 1-iodo-4-phenyl-
• Synonyms: 2-Butanone,1-iodo-4-phenyl;1-iodo-4-phenyl-2-butanone
• CAS NO: 352276-27-8
• Molecular Formula: C10H11IO
• Molecular Weight: 274.101
• Mol File: 352276-27-8.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-Butanone, 1-iodo-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butanone, 1-iodo-4-phenyl-(352276-27-8)
• EPA Substance Registry System: 2-Butanone, 1-iodo-4-phenyl-(352276-27-8)

Safety Data

• Hazardous Substances Data: 352276-27-8(Hazardous Substances Data)

Upstream product

• 2344-70-9 1-phenyl-3-butanol 
• 2550-26-7 4-Phenyl-2-butanone 
• 31984-10-8 1-bromo-4-phenylbutan-2-one 
• 645-45-4 hydrocinnamic acid chloride 
• 20845-80-1 1-chloro-4-phenylbutan-2-one 

Downstream Products

• 41162-19-0 dimethyl(2-oxo-4-phenylbutyl)phosphonate 
• 155206-00-1 bimatoprost 
• 38315-47-8 (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-((S)-(E)-3-hydroxy-5-phenylpent-1-enyl)-cyclopentyl]hept-5-enoic acid methyl ester 
• 477884-78-9 C₄₄H₈₂O₅Si₃ 
• 130209-82-4 latanoprost 
• 82102-19-0 2-amino-4-phenylbutylphosphonic acid 
• 128720-52-5 1-cyclohexyl-1-hydroxy-5-phenylpentan-3-one 
• 60836-01-3 5-hydroxy-6-methyl-1-phenylheptan-3-one 

Relevant articles and documents

Visible-Light-Triggered Iodinations Facilitated by Weak Electrostatic Interaction of N-Heterocyclic Carbenes

N-heterocyclic carbenes (NHCs) are well-known as ligands and organocatalysts, but there is no recognition for their catalytic role as a stabilizer through electrostatic interaction rather than electron donation. By utilizing the electrostatic interaction, we herein describe the success of a visible-light-triggered radical-radical cross-coupling of N-alkenoxypyridinium salts and NaI, giving a variety of α-iodo ketones. Computational studies characterize the stabilization role of NHCs.

One-pot synthesis of α-iodoketones from alcohols using ammonium iodide and Oxone in water

A novel protocol for the synthesis of α-iodoketones from alcohols has been developed. Using water as the reaction medium, ammonium iodide and Oxone was proven to be an efficient reagent system for this reaction and afforded the corresponding α-iodoketones in moderate to good yields. The generality of this reaction was demonstrated with various secondary alcohols such as benzylic alcohols and aliphatic alcohols (acyclic and cyclic).

Synthesis of (±)-bimatoprost

A general synthetic approach has been developed for the synthesis of a key intermediate (6) that can be elaborated into several ophthalmic prostaglandins and their derivatives. Using these strategy, we have obtained (±)-bimatoprost (1) and its analog, (±)-homobimatoprost (5). Copyright Taylor & Francis Group, LLC.