352535-83-2

Basic information

• Product Name: 5-CHLORO-2-FLUOROPHENYLBORONIC ACID
• Synonyms: 5-Chloro-2-fluorobenzeneboronicacid97%;5-Chloro-2-fluorophenylboronic Acid (contains varying aMounts of Anhydride);5-Chloro-2-fluorophenylbornic acid;AKOS BRN-0727;5-CHLORO-2-FLUOROBENZENEBORONIC ACID;5-CHLORO-2-FLUOROPHENYLBORONIC ACID;5-Chloro-2-fluorobenzeneboronic acid 97%
• CAS NO: 352535-83-2
• Molecular Formula: C6H5BClFO2
• Molecular Weight: 174.37
• EINECS: 1592732-453-0
• Product Categories: blocks;BoronicAcids;FluoroCompounds;Aryl;Boronic Acids;Boronic Acids and Derivatives;Organic boronic acid
• Mol File: 352535-83-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 122-127 °C(lit.)
• Boiling Point: 310.8 °C at 760 mmHg
• Flash Point: 141.8 °C
• Appearance: /
• Density: 1.41 g/cm³
• Vapor Pressure: 0.000252mmHg at 25°C
• Refractive Index: 1.533
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 7.35±0.58(Predicted)
• CAS DataBase Reference: 5-CHLORO-2-FLUOROPHENYLBORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLORO-2-FLUOROPHENYLBORONIC ACID(352535-83-2)
• EPA Substance Registry System: 5-CHLORO-2-FLUOROPHENYLBORONIC ACID(352535-83-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37-60
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 352535-83-2(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 352535-83-2 differently. You can refer to the following data:
1. suzuki reaction
2. Reactant involved in:Suzuki cross-coupling reactionsSynthesis of biaryl amides with muscarinic acetylcholine receptor subtype M1 agonistic activitySynthesis of kinesin spindle protein inhibitorsGABA α2/3 agonist preparation

InChI:InChI=1/C6H5BClFO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,10-11H

Upstream product

• 1996-30-1 2-bromo-4-chloro-1-fluorobenzene 
• 121-43-7 Trimethyl borate 
• 7732-18-5 water 
• 5419-55-6 Triisopropyl borate 
• 352-33-0 1-Chloro-4-fluorobenzene 

Relevant articles and documents

NEW COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME

The present invention relates to a novel compound and an organic luminescent device containing the novel compound in an organic compound layer, wherein the compound improves the life, efficiency, electrochemical stability, and thermal stability of the organic luminescent device. In chemical formula 1, R1 and R2 are selected from a group consisting of an alkyl group having 1-10 carbons and an aryl group having 6-30 carbons.

Design and application of a low-temperature continuous flow chemistry platform

A flow reactor platform technology applicable to a broad range of low temperature chemistry is reported. The newly developed system captures the essence of running low temperature reactions in batch and represents this as a series of five flow coils, each with independently variable volume. The system was initially applied to the functionalization of alkynes, Grignard addition reactions, heterocycle functionalization, and heteroatom acetylation. This new platform has then been used in the preparation of a 20-compound library of polysubstituted, fluorine-containing aromatic substrates from a sequential metalation-quench procedure and can be readily adapted to provide gaseous electrophile inputs such as carbon dioxide using a tube-in-tube reactor.