354-76-7Relevant articles and documents
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Hauptschein,M.,Braid,M.
, p. 2500 - 2505 (1961)
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Husted,Ahlbrecht
, p. 1605,1607 (1953)
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FLUOROALKYL-CONTAINING β,β'-TRICARBONYL COMPOUNDS: TAUTOMERISM AND REACTION WITH N-NUCLEOPHILES
Krokhalev, V. M.,Saloutin, V. I.,Romas', A. D.,Ershov, B. A.,Pashkevich, K. I.
, p. 316 - 322 (2007/10/02)
The tautomeric composition of α-polyfluoroacyl derivatives of acetylacetone and malonic ester has been established and it has been shown that with N-nucleophiles (ammonia, 1,2-ethylenediamine, o-phenylenediamine) these compounds undergo 'acid' decomposition with the elimination of the polyfluoroacyl group.With hydrazines, malonic ester derivatives react similarly but acetylacetone derivatives undergo cyclization into pyrazoles.The regiodirectivity of the interaction of fluoroalkyl-containing β,β'-tricarbonyl compounds with N-nucleophiles does not depend on their tautomeric composition and is determined by orbital control.
SYNTHESIS AND REACTIONS OF OXYGEN CONTAINING ORGANOFLUORINE COMPOUNDS. IX. REACTION OF POLYFLUOROALKYL KETONES WITH AMMONIA
Saloutina, L. V.,Zapevalov, A. Ya.,Kolenko, I. P.
, p. 2019 - 2024 (2007/10/02)
The reaction of polyfluoroalkyl ketones with ammonia at reduced temperature was studied.The products from addition of ammonia at the carbonyl group, i.e., geminal amino alkohols, were obtained.If there are chlorine and bromine atoms at the α position, the polyfluoroalkyl ketones dissociate under the influence of ammonia to carboxamides and polyhalogenoalkanes.
