355017-64-0

Basic information

• Product Name: 4-(4-HYDROXYMETHYL-2-METHOXY-5-NITROPHENOXY)BUTYRIC ACID
• Synonyms: 4-[4-HYDROXYMETHYL-2-METHOXY-5-NITROPHENOXY)BUTANOIC ACID;4-(4-HYDROXYMETHYL-2-METHOXY-5-NITROPHENOXY)BUTYRIC ACID;HYDROXYMETHYL PHOTOLINKER
• CAS NO: 355017-64-0
• Molecular Formula: C₁₂H₁₅NO₇
• Molecular Weight: 285.25
• Product Categories: Photolabile linker which carries a highly nucleophilic hydroxy group.
• Mol File: 355017-64-0.mol
• Article Data: 6

Chemical Properties

• Melting Point: 178-182 °C
• Appearance: /
• CAS DataBase Reference: 4-(4-HYDROXYMETHYL-2-METHOXY-5-NITROPHENOXY)BUTYRIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-HYDROXYMETHYL-2-METHOXY-5-NITROPHENOXY)BUTYRIC ACID(355017-64-0)
• EPA Substance Registry System: 4-(4-HYDROXYMETHYL-2-METHOXY-5-NITROPHENOXY)BUTYRIC ACID(355017-64-0)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 355017-64-0(Hazardous Substances Data)

Usage

General Description

4-(4-HYDROXYMETHYL-2-METHOXY-5-NITROPHENOXY)BUTYRIC ACID is a chemical compound with a complex structure that includes a butyric acid backbone with a hydroxymethyl, methoxy, and nitrophenoxy group attached at specific positions. It is a synthetic organic compound with potential pharmaceutical applications, and its precise chemical properties and uses are subject to ongoing research and development. This chemical may have potential as a drug candidate for various medical conditions, and further studies are needed to fully understand its pharmacological and therapeutic potential.

Upstream product

• 176375-42-1 4-(4-formyl-2-methoxy-5-nitrophenoxy)butanoic acid methyl ester 
• 176375-43-2 methyl 4-(4-(hydroxymethyl)-2-methoxy-5-nitrophenoxy)butanoate 
• 2426-84-8 4-(benzyloxy)-5-methoxy-2-nitrobenzaldehyde 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 260417-00-3 4-(hydroxymethyl)-2-methoxy-5-nitrophenol 
• 2454-72-0 6-nitrovanillin 
• 219931-67-6 ethyl 4-(4-formyl-2-methoxy-5-nitrophenoxy)butanoate 
• 141333-27-9 ethyl 4-(4-formyl-2-methoxyphenoxy)butanoate 
• 263758-69-6 4-(4-formyl-2-methoxy-5-nitrophenoxy)butanoic acid 
• 121-33-5 vanillin 

Downstream Products

• 1392043-87-6 4-(4-(acryloyloxymethyl)-2-methoxy-5-nitrophenoxy)butanoic acid 
• 848004-63-7 4-(4-hydroxymethyl-2-methoxy-5-nitro-phenoxy)-butyric acid allyl ester 

Relevant articles and documents

PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS

Photoactive probes and probe systems for detecting biological interactions are described. The photoactive probes include probes that combine both photocleavable and photoreactive moieties. The photoactive probe systems can include a first probe comprising a photocatalytic group and a second probe comprising a group that can act as a substrate for the reaction catalyzed by the photocatalytic group. The probes and probe systems can also include groups that can specifically bind to a binding partner on a biological entity of interest and a detectable group or a precursor thereof. The probes and probe systems can detect spatiotemporal interactions of proteins or cells. In some embodiments, the interactions can be detected in live cells. Also described are methods of detecting the biological interactions.

Photoresponsive multifunctional chemical crosslinking agent and preparation method and application thereof

The invention discloses a photoresponsive multifunctional chemical crosslinking agent. The structure of the crosslinking agent is shown in a formula I, wherein the definition of each substituent groupin the formula I is shown in the description. The prepa

Erratum: Photodegradable macromers and hydrogels for live cell encapsulation and release (Journal of the American Chemical Society (2012) 134 (13103-13107) DOI: 10.1021/ja305280w)

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