36073-90-2

Basic information

• Product Name: 2-(2-acetylphenyl)acetic acid
• Synonyms: 2-(2-acetylphenyl)acetic acid;(2-Acetyl-phenyl)-acetic acid
• CAS NO: 36073-90-2
• Molecular Formula: C₁₀H₁₀O₃
• Molecular Weight: 178.1846
• Mol File: 36073-90-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 347°C at 760 mmHg
• Flash Point: 177.9°C
• Appearance: /
• Density: 1.2g/cm³
• Vapor Pressure: 2.09E-05mmHg at 25°C
• Refractive Index: 1.551
• CAS DataBase Reference: 2-(2-acetylphenyl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-acetylphenyl)acetic acid(36073-90-2)
• EPA Substance Registry System: 2-(2-acetylphenyl)acetic acid(36073-90-2)

Safety Data

• Hazardous Substances Data: 36073-90-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H10O3/c1-7(11)9-5-3-2-4-8(9)6-10(12)13/h2-5H,6H2,1H3,(H,12,13)

Upstream product

• 195871-32-0 2-(2-acetylphenyl)acetaldehyde 
• 16535-88-9 (2-acetyk-phenyl)-acetic acid methyl ester 
• 83-33-0 inden-1-one 
• 64666-42-8 1-methyl-1-indanol 
• 767-60-2 3-Methylindene 

Downstream Products

• 127998-41-8 (2S,3S,10bR)-3-Hydroxymethyl-10b-methyl-2-phenyl-2,3,6,10b-tetrahydro-oxazolo[2,3-a]isoquinolin-5-one 
• 4385-59-5 1,4-Dihydro-1-methyl-2-benzopyran-3-on 
• 16535-88-9 (2-acetyk-phenyl)-acetic acid methyl ester 
• 95991-74-5 4-bromo-1-methyl-3-isochromanone 
• 95965-61-0 1-(N,N-dimethylaminomethyl)-3-methyl-1,3-dihydroisobenzofuran 
• 95965-86-9 1-methyl-4-(N'-phenylpiperazino)-3-isochroman 
• 95965-79-0 1-methyl-4-(N'-phenylpiperazino)-3-isochromanone 
• 127998-47-4 (2S,3S,6S,10bR)-6-[3-(tert-Butyl-dimethyl-silanyloxy)-propyl]-3-hydroxymethyl-6,10b-dimethyl-2-phenyl-2,3,6,10b-tetrahydro-oxazolo[2,3-a]isoquinolin-5-one 
• 128052-79-9 (2S,3S,6R,10bR)-6-[3-(tert-Butyl-dimethyl-silanyloxy)-propyl]-3-hydroxymethyl-6,10b-dimethyl-2-phenyl-2,3,6,10b-tetrahydro-oxazolo[2,3-a]isoquinolin-5-one 
• 127998-46-3 (2S,3S,6S,10bR)-6-Hex-5-enyl-3-hydroxymethyl-6,10b-dimethyl-2-phenyl-2,3,6,10b-tetrahydro-oxazolo[2,3-a]isoquinolin-5-one 
• 128052-78-8 (2S,3S,6R,10bR)-6-Hex-5-enyl-3-hydroxymethyl-6,10b-dimethyl-2-phenyl-2,3,6,10b-tetrahydro-oxazolo[2,3-a]isoquinolin-5-one 
• 127998-43-0 (2S,3S,6S,10bR)-6-Benzyl-3-hydroxymethyl-6,10b-dimethyl-2-phenyl-2,3,6,10b-tetrahydro-oxazolo[2,3-a]isoquinolin-5-one 
• 128052-75-5 (2S,3S,6R,10bR)-6-Benzyl-3-hydroxymethyl-6,10b-dimethyl-2-phenyl-2,3,6,10b-tetrahydro-oxazolo[2,3-a]isoquinolin-5-one 
• 127998-45-2 (2S,3S,6S,10bR)-6-Ethyl-3-hydroxymethyl-6,10b-dimethyl-2-phenyl-2,3,6,10b-tetrahydro-oxazolo[2,3-a]isoquinolin-5-one 

Relevant articles and documents

A novel tandem [2 + 2] cycloaddition-Dieckmann condensation with ynolate anions. Efficient synthesis of substituted cycloalkenones and naphthalenes via formal [n + 1] cycloaddition

A novel tandem [2 + 2] cycloaddition-Dieckmann condensation via ynolate anions is described. Ynolate anions are useful for the formation of reactive β-lactone enolates via a pathway not involving the enolization of the corresponding β-lactones. The [2 + 2] cycloaddition of ynolate anions with δ- or σ-keto esters, followed by Dieckmann condensation, gives bicyclic β-lactones, which are easily decarboxylated to produce synthetically useful 2,3-disubstituted cyclopentenones and cyclohexenones in one pot. This tandem reaction was applied to a novel, one-pot synthesis of highly substituted naphthalenes.

Asymmetric Synthesis of 4,4-Disubstituted 1-Naphthalenones. Diastereoselectivity as a Function of Metal Oxides

Chiral tricyclic lactam (5) was sequentionally metalated (LDA or LDA/zirconocene halides) and alkylated to give quaternary alkylation products (8) in 6-54:1 diastereomeric ratio.Reduction and hydrolysis furnish the title compound in three steps with >99 p