364038-73-3

Basic information

• Product Name: 2-Chloro-N-(6,7-dimethoxyquinazolin-4-yl)benzenesulphonamide
• CAS NO: 364038-73-3
• Molecular Weight: 379.824
• Mol File: 364038-73-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Chloro-N-(6,7-dimethoxyquinazolin-4-yl)benzenesulphonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-N-(6,7-dimethoxyquinazolin-4-yl)benzenesulphonamide(364038-73-3)
• EPA Substance Registry System: 2-Chloro-N-(6,7-dimethoxyquinazolin-4-yl)benzenesulphonamide(364038-73-3)

Safety Data

• Hazardous Substances Data: 364038-73-3(Hazardous Substances Data)

Upstream product

• 6961-82-6 2-chlorobenzenesulfonamide 
• 13790-39-1 6,7-dimethoxy-4-chloroquinazoline 

Relevant articles and documents

Bicyclic amine derivatives as inhibitors of class 1 receptor tyrosine kinases

Fused bicyclic amines of formula (1) are described wherein Ar is an aryl or heteroaryl group; Y is a —S(O2)— or —C(O)— group; R1 is a hydrogen or halogen atom or an alkyl, haloalkyl, alkoxy, haloalkoxy or cyano group; X is a nitrogen atom or a C(R1a) group where R1a is as defined for R1 and may be the same or different; W and Z are each a carbon atom and together with U form an optionally substituted five- or six-membered monocyclic aromatic or heteroaromatic group; and the salts, solvates, hydrates and N-oxides thereof. The compounds are able to inhibit the activity of Class I receptor tyrosine kinases and are of use in the prophylaxis and treatment of hyperproliferative disorders such as cancer, psoriasis, restenosis, atherosclerosis and fibrosis.