3733-29-7

Basic information

• Product Name: 1,3-Dioxane, 5,5-bis(broMoMethyl)-2-phenyl-
• Synonyms: 1,3-Dioxane, 5,5-bis(broMoMethyl)-2-phenyl-;5,5-Bis(broMoMethyl)-2-phenyl-1,3-dioxane
• CAS NO: 3733-29-7
• Molecular Formula: C₁₂H₁₄Br₂O₂
• Molecular Weight: 350.04636
• EINECS: -0
• Mol File: 3733-29-7.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-Dioxane, 5,5-bis(broMoMethyl)-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxane, 5,5-bis(broMoMethyl)-2-phenyl-(3733-29-7)
• EPA Substance Registry System: 1,3-Dioxane, 5,5-bis(broMoMethyl)-2-phenyl-(3733-29-7)

Safety Data

• Hazardous Substances Data: 3733-29-7(Hazardous Substances Data)

Usage

Explanation

Different sources of media describe the Explanation of 3733-29-7 differently. You can refer to the following data:
1. The molecular formula represents the number of atoms of each element present in a molecule of the compound.
2. Symmetrical compound
2. The compound has a balanced structure with two identical halves, making it symmetrical.
3. Contains two bromomethyl groups
3. Bromomethyl groups are functional groups containing a bromine atom and a methyl group (CH3) attached to the dioxane ring.
4. Dioxane ring
4. A six-membered heterocyclic organic compound composed of two oxygen atoms and four carbon atoms.
5. Crosslinking agent
5. Used in the production of polymers and resins to create a network of chemical bonds between polymer chains, improving the material's strength and stability.
6. Reagent in organic synthesis
6. Employed as a starting material or intermediate in the synthesis of various organic compounds.
7. Potential environmental hazard
7. The compound may have negative effects on the environment due to its chemical properties and potential for contamination.
8. Toxic effects on human health
8. Exposure to the compound can lead to adverse health effects, necessitating proper handling and safety precautions.
9. Proper handling and safety precautions
9. Due to its potential hazards, it is crucial to follow safety guidelines and protocols when working with this compound, such as using personal protective equipment and ensuring proper ventilation.

Upstream product

• 115-77-5 Pentaerythritol 
• 100-52-7 benzaldehyde 
• 3296-90-0 bis(bromomethyl)bis(hydroxymethyl)methane 

Downstream Products

• 142733-60-6 2,2‐diethyl 7‐phenyl‐6,8‐dioxaspiro[3.5]nonane‐2,2‐dicarboxylate 
• 1237542-07-2 diisopropyl 7-phenyl-6,8-dioxaspiro[3.5]nonane-2,2-dicarboxylate 
• 77614-64-3 7‐phenyl‐6,8‐dioxaspiro[3.5]nonane‐2,2‐dicarboxylic acid 
• 1053178-83-8 bis-(diethyl malonate)monobenzalpentaerythritol 

Relevant articles and documents

Nitroxide derivative of ROCK kinase inhibitor

The invention provides a small molecular compound of a NO donor. The small molecular compound is characterized in that the small molecular compound is a compound shown represented by structural formula I shown in the description, or a stereoisomer, a geometrical isomer, a tautomer, a racemate, a deuterated isotope derivative, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof; and in the formula I, ring A is a substituted or unsubstituted heteroaromatic ring, X is selected from (CH2)n, n is selected from 0, 1, 2 and 3, R is a substituent group of terminal -O-NO2, R is selected from hydrogen, a hydroxyl group, halogen, an amino group, a cyano group, a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkoxy group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted alkynyl group and a substituted or unsubstituted heteroalkyl group, and R and R are respectively and independently selected from hydrogen, a substituted or unsubstituted alkyl group, a substituted or unsubstituted naphthenic base or an amino protecting group, or R and R are connected to form a substituted or unsubstituted cyclic heteroalkyl group. The compound has a high-activity inhibition effect on ROCK kinase.

Host-guest complexes of cucurbit[8]uril with some pentaerythritol derivative guests

A series of first generation dendritic guests from pentaerythritol derivatives have been designed and synthesized. Investigation of the complex structures of cucurbit[8]uril (Q[8]) and the guests based on the 1H NMR technique have revealed that the host Q[8] selectively included different branch(es) of the first generation dendritic guests and formed inclusion complexes with different structural conformations. The experimental results obtained from electronic absorption spectroscopy showed that the 1:1 ratio of Q[8]-based host-guest inclusion complexes have moderate stability with an average formation constants of 104 L mol-1. The single crystal structures of some of the guests (g5 and g6) and Q[8]-guest complexes (Q[8]-g4 and Q[8]-g6) further confirm but in some cases contradict the research results of the 1H NMR technique and electronic absorption spectroscopy in aqueous solution. The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2011.

Cyclobutane-derived diamines: Synthesis and molecular structure

Cyclobutane diamines (i.e., cis- and trans-1,3-diaminocyclobutane, 6-amino-3-azaspiro[3.3]heptane, and 3,6-diaminospiro[3.3]heptane) are considered as promising sterically constrained diamine building blocks for drug discovery. An approach to the syntheses of their Boc-monoprotected derivatives has been developed aimed at the preparation of multigram amounts of the compounds. These novel synthetic schemes exploit classical malonate alkylation chemistry for the construction of cyclobutane rings. The conformational preferences of the cyclobutane diamine derivatives have been evaluated by X-ray diffraction and compared with the literature data on sterically constrained diamines, which are among the constituents of commercially available drugs.