37488-68-9 Usage
Chemical structure
A benzene ring with a methyl group at the 4-position and a cyclohex-2-enesulfonyl group attached to the 1-position.
Aromatic ring
Benzene ring
Alkyl group
Methyl group
Sulfonyl group
Cyclohex-2-enesulfonyl group
Molecular weight
Approximately 248.34 g/mol
Appearance
The compound is likely to be a solid or a viscous liquid, depending on the temperature and purity.
Solubility
It is expected to be soluble in organic solvents such as dichloromethane, ethyl acetate, and acetone.
Reactivity
The compound may exhibit unique reactivity and selectivity in certain chemical reactions due to its specific functional groups.
Organic synthesis
As a reagent or intermediate in the synthesis of various organic compounds.
Pharmaceutical research
In the development of new drugs or the production of specialty chemicals.
Safety
As with any chemical compound, appropriate safety measures should be taken when handling 1-(CYCLOHEX-2-ENESULFONYL)-4-METHYL-BENZENE, including the use of gloves, eye protection, and a well-ventilated workspace.
Storage
The compound should be stored in a cool, dry place, away from direct sunlight, and in a sealed container to prevent degradation or contamination.
Stability
It is important to consider the stability of the compound under various conditions, such as temperature, light exposure, and the presence of other reactive substances.
Purity
The purity of the compound can affect its reactivity and performance in chemical reactions, so it is essential to ensure that the compound is of high purity for research and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 37488-68-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,4,8 and 8 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 37488-68:
(7*3)+(6*7)+(5*4)+(4*8)+(3*8)+(2*6)+(1*8)=159
159 % 10 = 9
So 37488-68-9 is a valid CAS Registry Number.
37488-68-9Relevant articles and documents
Silver-Catalyzed C(sp3)-H Sulfonylation for the Synthesis of Benzyl Sulfones Using Toluene Derivatives and α-Amino Acid Sulfonamides
Kanyiva, Kyalo Stephen,Shibata, Takanori,Uchida, Kanako
, p. 1377 - 1384 (2021/06/06)
We describe a simple and practical protocol for the synthesis of benzyl sulfones using readily available toluene derivatives and α-amino acid sulfonamides. The reaction proceeds to afford a broad range of benzyl sulfones in moderate to high yields under silver catalysis. The mechanism possibly involves a Minisci-type formation of α-aminoalkyl radical, homolytic cleavage of a N-S bond to generate a sulfonyl radical, and coupling of sulfonyl radical with a benzyl radical formed via hydrogen abstraction by sulfate anion radical. The practicality of the present reaction is demonstrated by a gram-scale synthesis and one-step synthesis of anticancer-active compound. The mechanism studies are conducted using radical scavengers and deuterated toluene.
Iron (III) chloride-catalyzed direct sulfonylation of alcohols with sodium arenesulfinates
Reddy, M. Amarnath,Reddy, P. Surendra,Sreedhar
supporting information; experimental part, p. 1861 - 1869 (2010/10/21)
A new protocol for the direct sulfonylation of benzylic, allylic and homoallylic alcohols with sodium arenesulfinates is described by using iron (III) chloride as a catalyst and chlorotrimethylsilane as an additive. This method requires no preactivation o
Aluminum chloride-iron promoted coupling of sulfonyl chlorides with alkyl halides in aqueous media
Saikia, Promod,Laskar, Dhrubojyoti D.,Prajapati, Dipak,Sandhu, Jagir S.
, p. 512 - 513 (2007/10/03)
A simple and inexpensive procedure for the coupling of sulfonyl chlorides and alkyl halides with aluminum chloride-iron system at ambient temperature in high yield is achieved in aqueous media.
