380430-67-1Relevant articles and documents
ENHANCING AUTOPHAGY OR INCREASING LONGEVITY BY ADMINISTRATION OF UROLITHINS OR PRECURSORS THEREOF
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Sheet 29, (2014/01/17)
Disclosed are methods, compounds, and compositions useful for increasing autophagy and promoting longevity. The methods, compounds, and compositions relate to urolithins and urolithin precursors and use thereof. Certain urolithins are represented by Formula I, while certain urolithin precursors are represented by Formula IV. The urolithin may be urolithin A, urolithin B, urolithin C, or urolithin D. The urolithin precursor may be ellagic acid or an ellagitannin. The methods include in vivo, ex vivo, and in vitro uses of the compounds and compositions.
Nonsteroidal selective glucocorticoid modulators: The effect of C-10 substitution on receptor selectivity and functional potency of 5-allyl-2,5-dihydro-2,2,4-trimethyl-lh-[1]benzopyrano[3,4-f]quinolines
Kym, Philip R.,Kort, Michael E.,Coghlan, Michael J.,Moore, Jimmie L.,Tang, Rui,Ratajczyk, James D.,Larson, Daniel P.,Elmore, Steven W.,Pratt, John K.,Stashko, Michael A.,Douglass Falls,Lin, Chun W.,Nakane, Masake,Miller, Loan,Tyree, Curtis M.,Miner, Jeffery N.,Jacobson, Peer B.,Wilcox, Denise M.,Nguyen, Phong,Lane, Benjamin C.
, p. 1016 - 1030 (2007/10/03)
The preparation and characterization of a series of C-10 substituted 5-allyl-2,5-dihydro-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines as a novel class of selective ligands for the glucocorticoid receptor is described. Substitution at the C-10 positi
