3813-69-2

Basic information

• Product Name: p-Toluenesulfonic acid 1-methylbutyl ester
• Synonyms: 2-Pentyl tosylate;4-Methylbenzenesulfonic acid 1-methylbutyl ester;p-Toluenesulfonic acid 1-methylbutyl ester;Benzenesulfonic acid, 4-Methyl-, 1-Methylbutyl ester
• CAS NO: 3813-69-2
• Molecular Formula: C₁₂H₁₈O₃S
• Molecular Weight: 242.33
• Mol File: 3813-69-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 343.9°C at 760 mmHg
• Flash Point: 161.8°C
• Appearance: /
• Density: 1.1g/cm³
• Vapor Pressure: 0.000135mmHg at 25°C
• Refractive Index: 1.502
• CAS DataBase Reference: p-Toluenesulfonic acid 1-methylbutyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: p-Toluenesulfonic acid 1-methylbutyl ester(3813-69-2)
• EPA Substance Registry System: p-Toluenesulfonic acid 1-methylbutyl ester(3813-69-2)

Safety Data

• Hazardous Substances Data: 3813-69-2(Hazardous Substances Data)

Usage

General Description

p-Toluenesulfonic acid 1-methylbutyl ester is a chemical compound with the formula C11H16O3S. It is an ester of p-toluenesulfonic acid and 1-methylbutanol. p-Toluenesulfonic acid 1-methylbutyl ester is used as a strong acid catalyst in a variety of organic reactions, such as esterification, transesterification, and alkylation. It is also a commonly used reagent in the synthesis of pharmaceuticals and agrochemicals. p-Toluenesulfonic acid 1-methylbutyl ester is a colorless to light yellow liquid with a characteristic odor, and it should be handled with care due to its corrosive nature.

InChI:InChI=1/C12H18O3S/c1-4-5-11(3)15-16(13,14)12-8-6-10(2)7-9-12/h6-9,11H,4-5H2,1-3H3

Upstream product

• 6032-29-7 (+/-)-2-pentanol 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 29182-76-1 p-N,N-Dimethylaminophenyl-2-pentylsulfon 
• 29182-85-2 p-Bromphenyl-2-pentylsulfid 
• 646-04-8 (E)-pent-2-ene 
• 109-67-1 1-penten 
• 2432-40-8 Pent-2-yl-thioacetat 
• 2084-19-7 pentane-2-thiol 
• 117-47-5 diethyl (1-methylbutyl)malonate 
• 1339803-77-8 4-(4-(4-(4-methoxyphenyl)piperazin-1-yl)phenyl)-1-(pentan-2-yl)-1H-1,2,4-triazol-5(4H)-one 
• 1339803-83-6 4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1-(pentan-2-yl)-1H-1,2,4-triazol-5(4H)-one 
• 1339803-69-8 cis-(2S,4R)-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylbutyl)-3H-1,2,4-triazol-3-one 
• 29182-81-8 p-Nitrophenyl-2-pentylsulfon 
• 29182-82-9 2,4,6-Trimethylphenyl-2-pentylsulfon 
• 29182-77-2 p-Methoxy-phenyl-2-pentylsulfon 
• 29182-80-7 p-Bromphenyl-2-pentylsulfon 

Relevant articles and documents

Regiospecific S-aminoalkylation of 5-substituted 6-hydroxy-2-thiouracil derivatives in the synthesis of structural analogs of isothiobarbamine

Regiospecific S-monoaminoalkylation of 5-substituted derivatives of 6-hydroxy-2-thiouracil with free N,N-dialkyl-N-(2-chloroethyl)amines in anhydrous PriOH was described for the first time. In compliance with the rules and regulations of green chemistry, this approach was used to synthesize a number of structural analogs of isothiobarbamine in high yield and purity, which are potential synthetic actoprotectors of immediate action.

Cobalt-Catalyzed Silylcarbonylation of Unactivated Secondary Alkyl Tosylates at Low Pressure

A catalytic preparation of silyl enol ethers from unactivated secondary alkyl tosylates is reported. An inexpensive cobalt catalyst is used under mild conditions with low pressures of carbon monoxide. Nucleophilic, anionic cobalt carbonyls facilitate the catalytic activation of a range of alkyl tosylates. The silylcarbonylation offers a practical approach to synthetically valuable silyl enol ethers from simple starting materials.

ITRACONAZOLE ANALOGS AND USE THEREOF

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