3823-13-0

Basic information

• Product Name: 2-cyclohexyl-2,3-dihydro-1H-isoindol-1-one
• Synonyms: 2-cyclohexyl-2,3-dihydro-1H-isoindol-1-one
• CAS NO: 3823-13-0
• Molecular Weight: 215.295
• Mol File: 3823-13-0.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 2-cyclohexyl-2,3-dihydro-1H-isoindol-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyclohexyl-2,3-dihydro-1H-isoindol-1-one(3823-13-0)
• EPA Substance Registry System: 2-cyclohexyl-2,3-dihydro-1H-isoindol-1-one(3823-13-0)

Safety Data

• Hazardous Substances Data: 3823-13-0(Hazardous Substances Data)

Upstream product

• 2133-65-5 N-cyclohexylphthalimide 
• 108-91-8 cyclohexylamine 
• 108-94-1 cyclohexanone 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 349395-89-7 2-bromo-N-cyclohexyl-N-methylbenzamide 
• 643-79-8 o-phthalic dicarboxaldehyde 
• 2417-73-4 methyl 2-bromomethylbenzoate 
• 931-53-3 Cyclohexyl isocyanide 
• 6630-33-7 ortho-bromobenzaldehyde 
• 89-71-4 2-Methyl-benzoic acid methyl ester 
• 34040-62-5 o-(chloromethyl)benzoic acid methyl ester 
• 4383-25-9 N-benzylcyclohexylamine 
• 119-67-5 o-carboxybenzaldehyde 
• 91-13-4 α,α'-dibromo-o-xylene 

Relevant articles and documents

Steric effect of carboxylic acid ligands on Pd-catalyzed C-H activation reactions

Various carboxylic acids with different substitution patterns were used as ligands in intra- and intermolecular Pd-catalyzed C-H activation reactions to investigate steric effect of the ligands. Bulky carboxylic acids suppress deactivation of Pd catalysts

Divergent Reaction of Isocyanides with o-Bromobenzaldehydes: Synthesis of Ketenimines and Lactams with Isoindolinone Cores

A divergent reaction of isocyanides with o-bromobenzaldehydes for the synthesis of isoindolinone-derived ketenimines and lactams was disclosed. The reaction features readily available reactants, relatively mild conditions, and high yields of products. Ketenimines could be applied in further transformations for access to other functional molecules. A mechanism study showed that the palladium-migration/imine-insertion process was the key step in this reaction.

One-pot synthesis of pyrrolidones from levulinic acid and amines/nitroarenes/nitriles over the Ir-PVP catalyst

The synthesis of pyrrolidones via reductive amination of levulinic acid with aniline was examined over polypyrrolidone-stabilized metal nanoparticle catalysts. Among them, Ir metal was the most effective and applicable for the reductive amination of levulinic acid with nitroarenes/nitriles. Importantly, this catalyst was used for the one-pot synthesis of the anti-inflammatory drug indoprofen from 2-formylbenzoic acid and 2-(4-nitrophenyl)propanoic acid.