38418-12-1

Basic information

• Product Name: [1,1'-biphenyl]-4-ylmethyl benzoate
• Synonyms: [1,1'-biphenyl]-4-ylmethyl benzoate
• CAS NO: 38418-12-1
• Molecular Weight: 288.346
• Mol File: 38418-12-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: [1,1'-biphenyl]-4-ylmethyl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1'-biphenyl]-4-ylmethyl benzoate(38418-12-1)
• EPA Substance Registry System: [1,1'-biphenyl]-4-ylmethyl benzoate(38418-12-1)

Safety Data

• Hazardous Substances Data: 38418-12-1(Hazardous Substances Data)

Upstream product

• 5728-52-9 (4-biphenylyl)acetic acid 
• 6597-18-8 (dibenzoyloxyiodo)benzene 
• 591-50-4 iodobenzene 
• 3597-91-9 biphenyl-4-yl methanol 
• 13939-06-5 molybdenum hexacarbonyl 
• 611-74-5 N,N-dimethylbenzamide 
• 98-88-4 benzoyl chloride 
• 93-97-0 benzoic acid anhydride 
• 54769-36-7 N-benzoyloxybenzotriazole 
• 90713-03-4 C₁₄H₁₅NO₆ 
• 20893-02-1 O-Benzoyl-isonitrosomalonsaeure-dinitril 
• 139259-95-3 N-(acetyloxy)-N-(([1,1'-biphenyl]-4-ylmethyl)oxy)benzamide 

Relevant articles and documents

Photoredox-Catalyzed Benzylic Esterification via Radical-Polar Crossover

Photoredox-catalyzed C-O bond formation reactions are reported. The decarboxylative esterification reaction allows the conversion of a variety of arylacetic acids into the corresponding benzyl carboxylates. Furthermore, the use of (diacetoxyiodo)benzene allows the conversion of the benzylic C-H bond through hydrogen atom transfer. The reactions were applied to the divergent transformation of pharmaceuticals via decarboxylative or C-H esterification reactions.

Esterification of Tertiary Amides by Alcohols Through C?N Bond Cleavage over CeO2

CeO2 has been found to promote ester forming alcoholysis reactions of tertiary amides. The present catalytic system is operationally simple, recyclable, and it does not require additives. The esterification process displays a wide substrate scope (>45 examples; up to 93 % isolated yield). Results of a density functional theory (DFT) study combined with in situ FT-IR observations indicate that the process proceeds through rate limiting addition of a CeO2 lattice oxygen to the carbonyl group of the adsorbed acetamide species with energy barrier of 17.0 kcal/mol. This value matches well with experimental value (17.9 kcal/mol) obtained from analysis of the Arrhenius plot. Further studies by in situ FT-IR and temperature programmed desorption using probe molecules demonstrate that both acidic and basic properties are important, and consequently, CeO2 showed the best performance for the C?N bond cleavage reaction.

Investigation of benzoyloximes as benzoylating reagents: Benzoyl-Oxyma as a selective benzoylating reagent

Hydroxybenzotriazole (HOBt) and HOBt-derived reagents have been classified as Class I explosives, with restrictions on their transportation and storage. We explored a range of benzoylated oxime-based reagents as alternatives to benzoyloxybenzotriazole (BBTZ) for the selective benzoylation of carbohydrate polyols. Benzoylated oximes derived from 2-hydroximino-malononitrile, ethyl 2-hydroximino-2-cyanoacetate (Oxyma), and tert-butyl 2-hydroximino-2-cyanoacetate were most effective for benzoylation of a simple primary alcohol, with yields approaching that obtained for BBTZ. When applied to carbohydrate diols, the most effective reagent was identified as benzoyl-Oxyma. Benzoyl-Oxyma is a highly crystalline, readily prepared alternative to BBTZ, useful in the selective benzoylation of carbohydrate polyols.