38602-53-8

Basic information

• Product Name: Calliterpenone
• Synonyms: (5α,9α,10β,16R)-16,17-Dihydroxykaurane-3-one;Calliterpenone;(5α,9α,10β)-16,17-Dihydroxykauran-3-one
• CAS NO: 38602-53-8
• Molecular Formula: C₂₀H₃₂O₃
• Molecular Weight: 320.46628
• Mol File: 38602-53-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Calliterpenone(CAS DataBase Reference)
• NIST Chemistry Reference: Calliterpenone(38602-53-8)
• EPA Substance Registry System: Calliterpenone(38602-53-8)

Safety Data

• Hazardous Substances Data: 38602-53-8(Hazardous Substances Data)

Usage

General Description

Calliterpenone is a natural chemical compound that belongs to the class of terpenoid compounds. It is found in a variety of plants and exhibits diverse biological activities. Calliterpenone has been isolated from the aerial parts of Callitris species, which are evergreen trees native to Australia. Calliterpenone has been identified as a potent inhibitor of the enzyme squalene synthase, important for the biosynthesis of sterols in organisms. It also possesses significant antimicrobial activity, particularly against the bacteria Staphylococcus aureus and the fungus Candida albicans. Additionally, calliterpenone has been reported to exhibit antioxidant and cytotoxic properties, making it a compound of interest for potential pharmaceutical and medicinal applications.

Upstream product

• 30211-82-6 ent-17-acetoxy-16β-hydroxykauran-3-one 
• 20460-65-5 ent-kaurene-16-en-3-one 
• 548486-51-7 (16R)-16,17-epoxy-ent-kauran-3-one 
• 30256-96-3 (16R)-16-hydroxy-17-{[(4-methylphenyl)sulfonyl]oxy}-ent-kauran-3-one 
• 19891-40-8 ent-3β-hydroxykaur-16-ene 
• 38602-53-8 (16R)-16,17-dihydroxy-ent-kauran-3-one 

Downstream Products

• 16836-28-5 ent-16,17-dihydroxy-16β-kauran-3-one 
• 30256-96-3 (16R)-16-hydroxy-17-{[(4-methylphenyl)sulfonyl]oxy}-ent-kauran-3-one 
• 19891-29-3 C₂₀H₃₄O₃ 

Relevant articles and documents

Sesquiterpenes and phenolic compounds from achillea clypeolata

The investigation of a dichloromethane extract of flower heads of Achillea clypeolata collected in Bulgaria led to the isolation of one guaiane (4,10,11-trihydroxy-guaiane, 1), four eudesmanes (4(15)-eudesmene-1β, 11-diol, 2, clypeotriol, 3, 3-epi-clypeotriol, 4, cryptomeridiol, 5), one diterpene (sugeroside, 6) and two phenolic compounds (centaureidin, 7 and scopoletin, 8). Their structures were elucidated by UV/vis, EI- and CI-MS as well as by one- and two-dimensional NMR experiments. 4,10,11-Trihydroxy-guaiane (1) and 3-epi-clypeotriol (4) are reported here for the first time.

GUAIANOLIDES AND HELIANGOLIDES FROM HYMENOPAPPUS NEWBERRYI

The aerial parts of Hymenopappus newberryi afforded two heliangolides, two thymol derivatives, as well as two new guaianolides and a trans,trans-germacranolide closely related to hiyodorilactone A.Furthermore, the ent-kaurene derivative abbeokutone was present.These results are of chemotaxonomic interest.Key Word Index - Hymenopappus newberryi; Compositae; sesquiterpene; lactones; guaianolides; heliangolides; ent-kaurene derivative; chemotaxonomy.