398456-82-1

Basic information

• Product Name: 3-BROMO-2,6-DIFLUOROBENZALDEHYDE
• Synonyms: 3-BROMO-2,6-DIFLUOROBENZALDEHYDE;3-Bromo-2,6-difluorobenzaldehyde 98%;3-Bromo-2,6-difluorobenzaldehyde98%
• CAS NO: 398456-82-1
• Molecular Formula: C₇H₃BrF₂O
• Molecular Weight: 221
• Mol File: 398456-82-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 53-57°C
• Boiling Point: 223℃
• Flash Point: 89℃
• Appearance: /
• Density: 1.758
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive: Air Sensitive
• CAS DataBase Reference: 3-BROMO-2,6-DIFLUOROBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-2,6-DIFLUOROBENZALDEHYDE(398456-82-1)
• EPA Substance Registry System: 3-BROMO-2,6-DIFLUOROBENZALDEHYDE(398456-82-1)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 398456-82-1(Hazardous Substances Data)

Usage

Uses

3-Bromo-2,6-difluorobenzaldehyde is used as a pharmaceutical intermediate.

Upstream product

• 348-57-2 2,4-difluorobromobenzene 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 438050-05-6 (3-bromo-2,6-difluorophenyl)methanol 
• 1198273-72-1 6-[3-(tert-Butyldimethylsilanyloxymethyl)-2,4-difluorophenyl]-2-chloro-imidazo[1,2-a]pyridine 
• 1198567-67-7 [2,6-difluoro-3-(3-methyl-2-thien-2-ylimidazo[1,2-a]pyridin-6-yl)phenyl]methanol 
• 1198211-11-8 5-[3-(tert-butyldimethylsilanyloxymethyl)-2,4-difluorophenyl]pyridin-2-ylamine 
• 1198567-68-8 6-[3-(tert-butyldimethylsilanyloxymethyl)-2,4-difluorophenyl]-3-methyl-2-thien-2-ylimidazo[1,2-a]pyridine 
• 1198273-66-3 {3-[2-(3,4-Difluorophenyl)imidazo[1,2-a]pyridin-6-yl]-2,6-difluorophenyl}methanol 
• 1198273-67-4 6-[3-(tert-Butyldimethylsilanyloxymethyl)-2,4-difluorophenyl]-2-(3,4-difluorophenyl)imidazo[1,2-a]pyridine 
• 1198274-45-1 C₂₈H₃₁F₂N₃O₂Si 
• 1198274-20-2 N-{3-[6-(2,4-difluoro-3-hydroxymethylphenyl)imidazo[1,2-a]pyridin-2-yl]phenyl}acetamide 
• 1193348-29-6 5-(3-bromo-2,6-difluorophenyl)-4-chloro-1-(4-chlorophenyl)-1H-imidazole 

Relevant articles and documents

ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS

The present invention relates to a compound represented by formula I: and pharmaceutically acceptable salts thereof. The compounds of formula I are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

AMIDE COMPOUND

A compound having GPR52 agonist activity or a salt thereof is provided. The compound can be provided as a preventive/therapeutic agent for schizophrenia or the like. The compound is represented by the following formula: wherein A represents —CONRa— or —NRaCO—, Ra represents a hydrogen atom or the like,B represents a hydrogen atom or the like,a ring Cy1 represents a six-membered aromatic ring which may have one or more substituents in addition to a group represented by -A-B,a ring Cy2 represents a six-membered ring which may be substituted with a halogen atom or the like,a ring Cy3 represents a five- or six-membered ring which may have one or more substituents;X represents C1-2 alkylene or the like,m represents an integer of 0 to 2, anda ring Cy4 represents a six-membered aromatic ring which may have one or more substituents.