438050-05-6

Basic information

• Product Name: (3-broMo-2,6-difluorophenyl)Methanol
• Synonyms: (3-broMo-2,6-difluorophenyl)Methanol
• CAS NO: 438050-05-6
• Molecular Formula: C₇H₅BrF₂O
• Molecular Weight: 223.0148064
• Mol File: 438050-05-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 249.8±35.0 °C(Predicted)
• Appearance: /
• Density: 1.744±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 13.33±0.10(Predicted)
• CAS DataBase Reference: (3-broMo-2,6-difluorophenyl)Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (3-broMo-2,6-difluorophenyl)Methanol(438050-05-6)
• EPA Substance Registry System: (3-broMo-2,6-difluorophenyl)Methanol(438050-05-6)

Safety Data

• Hazardous Substances Data: 438050-05-6(Hazardous Substances Data)

Usage

General Description

"(3-bromo-2,6-difluorophenyl)methanol, also known as 3-Bromo-2,6-difluorobenzylic alcohol, is a chemical compound which belongs to the class of organic compounds, particularly the class of phenols and derivatives. Its molecules are characterized by a benzene ring bearing a bromo group, two fluorine atoms, and a methanol group. The bromo group is attached to the third carbon, while the fluorine atoms are attached to the second and sixth carbons of the benzene ring, and the methanol group is attached directly to the benzene ring. (3-broMo-2,6-difluorophenyl)Methanol is used in various chemical reactions as an important intermediate and may contribute to the synthesis of more complex chemical compounds. Due to its aromatic fluorinated structure, it may showcase properties such as high stability and reactivity applicable in pharmaceutical and chemical industries.

Upstream product

• 398456-82-1 3-bromo-2,6-difluoro-benzaldehyde 
• 348-57-2 2,4-difluorobromobenzene 

Downstream Products

• 1198274-20-2 N-{3-[6-(2,4-difluoro-3-hydroxymethylphenyl)imidazo[1,2-a]pyridin-2-yl]phenyl}acetamide 
• 1198274-45-1 C₂₈H₃₁F₂N₃O₂Si 
• 1198273-67-4 6-[3-(tert-Butyldimethylsilanyloxymethyl)-2,4-difluorophenyl]-2-(3,4-difluorophenyl)imidazo[1,2-a]pyridine 
• 1198273-66-3 {3-[2-(3,4-Difluorophenyl)imidazo[1,2-a]pyridin-6-yl]-2,6-difluorophenyl}methanol 
• 1198567-68-8 6-[3-(tert-butyldimethylsilanyloxymethyl)-2,4-difluorophenyl]-3-methyl-2-thien-2-ylimidazo[1,2-a]pyridine 
• 1198211-11-8 5-[3-(tert-butyldimethylsilanyloxymethyl)-2,4-difluorophenyl]pyridin-2-ylamine 
• 1198567-67-7 [2,6-difluoro-3-(3-methyl-2-thien-2-ylimidazo[1,2-a]pyridin-6-yl)phenyl]methanol 
• 1198273-72-1 6-[3-(tert-Butyldimethylsilanyloxymethyl)-2,4-difluorophenyl]-2-chloro-imidazo[1,2-a]pyridine 
• 1198211-10-7 (3-Bromo-2,6-difluorobenzyloxy)(tert-butyl)dimethylsilane 
• 438050-10-3 (R)-2-ethyl-piperazine-1,4-dicarboxylic acid 4-tert-butyl ester 1-(3-bromo-2,6-difluoro-benzyl)ester 

Relevant articles and documents

ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS

The present invention relates to a compound represented by formula I: and pharmaceutically acceptable salts thereof. The compounds of formula I are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

POLYSUBSTITUTED 2-ARYL-6-PHENYLIMIDAZO[1,2-A]PYRIDINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC USE THEREOF

Compounds of formula (I): wherein R, R1, R2, R3, R4, and X are as defined in the disclosure, or an acid addition salt thereof, and the therapeutic use and process of synthesis thereof.

POLYSUBSTITUTED DERIVATIVES OF 2-ARYL-6-PHENYL-IMIDAZO[1,2-a]PYRIDINES, AND PREPARATION AND THERAPEUTIC USE THEREOF

Compounds of formula (I): wherein R1, R2, R3, R4 and X are as defined in the disclosure, or an acid addition salt thereof, and the therapeutic use and process of synthesis thereof.