40247-51-6

Basic information

• Product Name: bromo-4 (ethyl-1 hydroxy-1 propyl)-3 pyridine
• Synonyms: bromo-4 (ethyl-1 hydroxy-1 propyl)-3 pyridine
• CAS NO: 40247-51-6
• Molecular Weight: 244.131
• Mol File: 40247-51-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: bromo-4 (ethyl-1 hydroxy-1 propyl)-3 pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: bromo-4 (ethyl-1 hydroxy-1 propyl)-3 pyridine(40247-51-6)
• EPA Substance Registry System: bromo-4 (ethyl-1 hydroxy-1 propyl)-3 pyridine(40247-51-6)

Safety Data

• Hazardous Substances Data: 40247-51-6(Hazardous Substances Data)

Upstream product

• 626-55-1 3-Bromopyridine 
• 96-22-0 pentan-3-one 
• 4111-54-0 lithium diisopropyl amide 

Relevant articles and documents

REACTION DE LA BROMO-3 PYRIDINE AVEC LE DIISOPROPYLAMIDURE DE LITHIUM. MECANISMES DE METALLATION ET DE MIGRATION D'HALOGENE. REGIOSELECTIVITE DE L'ADDITION POLAIRE SUR LA PYRIDYNE-3,4

3-bromo pyridine behaviour towards lithium diisopropyl amide (LDA) in THF is studied.A careful study of the experimental conditions point to a metallation reaction in a position 4 and a "halogen dance" mechanism with isomerisation into a 4-bromo pyridine.Conversion into diisopropylamino compounds occurs simultaneously with a 3 oriented elimination-addition (EA) reaction from transient isomeric lithio-derivatives and a competing addition-elimination (AE) mechanism from the in situ formed 4-bromo pyridine.