40691-33-6Relevant articles and documents
Bivalent palladium complexes, conjugated aromatic compound and conjugated aromatic hydrocarbon polymer
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Paragraph 0209; 0210; 0215; 0221; 0226; 0231; 0236, (2018/02/04)
The invention provides a bivalent palladium complex having a structure in a formula (I), a formula (II) or a formula (III) and a preparation method of the bivalent palladium complex. The invention also provides a conjugate aromatic hydrocarbon compound ha
Synthesis, characterization, in vitro cytotoxicity and anti-inflammatory activity of palladium(II) complexes with tertiary phosphines and heterocyclic thiolates: Crystal structure of [PdC28H19N8PS2]
Shaheen, Farkhanda,Badshah, Amin,Gielen, Marcel,Gieck, Christine,Jamil, Mariyam,de Vos, Dick
, p. 1117 - 1126 (2008/04/13)
The new four-coordinated mononuclear palladium(II) complexes 1-9 with chelating heterocyclic thiolates and tertiary phosphines with general formula [Pd(L)nCl(R′R2P)] (L = Pym2SH (pyrimidine-2-thiolate), Pur6SH (purine-6-thiolate), Py2SH (pyridine-2-thiolate), R3P = PPh3, P(o-tolyl)3, PPh2Cl), n = 1, 2) have been synthesized by the direct reaction of [PdCl2(R′R2P)2] with polyfunctional heterocyclic thiolates which display a wide variety of coordinations. These compounds were characterized by elemental analysis, FT-IR and multinuclear (1H, 13C and 31P) NMR. The X-ray diffraction study of non-ionic compound 5 showed that the thiolate acts as unidentate and that the chelating (-N,S) ligand adopts a slightly distorted square planar geometry around the palladium atom. In vitro the anti-inflammatory inhibition of compounds 1-9 was 10-15% greater than that of the standard drug Declofenac. Compounds 1 and 4 showed mostly a moderate to low cytotoxicity against seven human tumor cell lines whereas compound 3 was somewhat more active.
Special effects of ortho-isopropylphenyl groups. Diastereoisomerism in platinum(II) and palladium(II) complexes of helically chiral PAr3 ligands
Baber, R. Angharad,Orpen, A. Guy,Pringle, Paul G.,Wilkinson, Matthew J.,Wingad, Richard L.
, p. 659 - 667 (2007/10/03)
The coordination chemistry of the four phosphines, P{C6H 3(o-CH3)(p-Z)}3 where Z = H (1a) or OMe (1b) and P{C6H3(o-CHMe2)(p-Z)}3 Z = H (1c) or OMe (1d) with platinum(II) and palladium(II) is reported. Mononuclear complexes trans-[PdCl2L2] (L = 1a,b) and trans-[PtCl 2L2] (L = 1a-c) have been prepared and the crystal structures of trans-[PdCl2(1b)2] and trans-[PtCl 2(1c)2] as their dichloromethane solvates have been determined. The structures show that in these complexes, the ligands adopt g+g+a conformations. Examination of the Cambridge Structural Database confirms this to be one of only two conformer types that tri-o-tolylphosphines adopt and the only viable conformer in 4 and 6 coordinate complexes. The binuclear complexes trans-[Pd2Cl4L 2] (L = 1c,d) are formed even when an excess of the bulky 1c,d is used in the synthesis and the crystal structure of trans-[Pd2Cl 4(1c)2] as its chloroform solvate is reported. Reaction of [PtCl2(NCBu1)2] with 1b-d in refluxing toluene gave the cycloplatinated species [Pt2Cl2(L - H) 2] where L - H is phosphine 1b-d deprotonated at one of the ortho-methyl carbon atoms. Variable temperature 31P and 1H NMR spectroscopy reveals that all the complexes reported are fluxional. The processes are analysed in terms of restricted P-C and P-M rotations that give rise to diastereoisomeric rotamers because of the helically chiral orientations of the aryl substituants. For the complexes of the bulky ligands 1c,d, rotation about the P-C bond is slow on the NMR timescale even up to 75°C. The crystal structure of the cyclometallated complex [Pt2Cl2(1d - H)2] has been determined. The Royal Society of Chemistry 2005.
