4075-20-1

Basic information

• Product Name: 14A-HYDROXYTESTOSTERONE--DEA*SCHEDULE II I ITEM
• Synonyms: 14A-HYDROXYTESTOSTERONE--DEA*SCHEDULE II I ITEM;14-hydroxytestosterone;4-Androstene-14α,17β-diol-3-one;14alpha,17beta-Dihydroxyandrost-4-en-3-one
• CAS NO: 4075-20-1
• Molecular Formula: C₁₉H₂₈O₃
• Molecular Weight: 304.4238
• Mol File: 4075-20-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 469.5°Cat760mmHg
• Flash Point: 251.8°C
• Appearance: /
• Density: 1.19g/cm³
• Vapor Pressure: 1.37E-07mmHg at 25°C
• Refractive Index: 1.468
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 14A-HYDROXYTESTOSTERONE--DEA*SCHEDULE II I ITEM(CAS DataBase Reference)
• NIST Chemistry Reference: 14A-HYDROXYTESTOSTERONE--DEA*SCHEDULE II I ITEM(4075-20-1)
• EPA Substance Registry System: 14A-HYDROXYTESTOSTERONE--DEA*SCHEDULE II I ITEM(4075-20-1)

Safety Data

• Hazard Codes: Xn
• Statements: 63-20/21/22-40
• Safety Statements: 22-36
• Hazardous Substances Data: 4075-20-1(Hazardous Substances Data)

Usage

Classification

Synthetic androgen and anabolic steroid

Schedule

DEA Schedule II Controlled Substance

Potential for Abuse

High

Medical Use

Not typically accepted in the United States

Derivation

Derived from testosterone

Common Use

Performance-enhancing drug for athletes and bodybuilders

Effects

Improves muscle mass and strength

Health Risks

Liver damage, cardiovascular issues, and hormonal imbalances

Regulation

Strictly regulated by the DEA

Production

Controlled and monitored

Distribution

Requires proper licensing and oversight

Possession

Limited to authorized individuals and entities

Legal Consequences

Illegal possession or distribution can result in severe penalties

InChI:InChI=1/C14H28O3/c15-13-11-9-7-5-3-1-2-4-6-8-10-12-14(16)17/h15H,1-13H2,(H,16,17)

Upstream product

• 58-22-0 testosterone 
• 53-43-0 dehydroepiandrosterone 
• 521-17-5 5-androstenediol 
• 63-05-8 Androstenedione 
• 315-37-7 testosterone heptanoate 

Downstream Products

• 564-63-6 14-hydroxy-4-androstene-3,17-dione 

Relevant articles and documents

Biotransformation of testosterone by Ulocladium chartarum MRC 72584

The incubation of testosterone 1 with Ulocladium chartarum MRC 72584 has been reported. U. chartarum MRC 72584 hydroxylated testosterone 1 at C-7β, C-6β, C-14α and C-12β, accompanied by a 5α-reduction and oxidations at C-6 and at C-17.

Biotransformation of testosterone and testosterone heptanoate by four filamentous fungi

The microbial transformations of testosterone and testosterone heptanoate by four fungi: Absidia griseolla var. igachii PTCC 5260, Acremonium chrysogenu PTCC 5271, Fusarium fujikuroi PTCC 5144, and Fusarium solani complex PTCC 5285 were investigated for the first time. Incubation of testosterone heptanoate with F. fujikuroi and F. solani yielded three metabolites, which were isolated and characterized as testosterone, androst-4-ene-3,17-dione, and 6β-hydroxy testosterone. 6β-Hydroxy testosterone was the major metabolite obtained from testosterone heptanoate biotransformation by two fungal species. A. griseolla and A. chrysogenu produced 14α-hydroxy testosterone as major metabolite, together with testosterone and 6β-hydroxy testosterone in lower yields. The biotransformation of testosterone by F. fujikuroi and A. griseolla was also investigated in order to examine the influence of the ester group on the course of transformation. Androst-4-ene-3,17-dione was only identified in the biotransformation of testosterone by F. fujikuroi. The same product was observed in incubation of testosterone by A. griseolla, together with 14α-hydroxy testosterone in very low yield. Furthermore, time course study was also carried out in order to examine the formation of metabolites as a function of time, which was determined by HPLC. The structures of compounds were determined by their comprehensive spectroscopic analysis and comparison with literature data.

Hydroxylation of androst-4-ene-3,17-dione with the aid of Curvularia lunata fungus

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